SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		5 / 12 GLY A  98
GLY A 109
ASN A  95
THR A 107
GLU A 158
 None
 1.25A 2vdvE-5h5zA:
undetectable		 2vdvE-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		5 / 11 GLY A  98
GLY A 109
ASN A  95
THR A 107
GLU A 158
 None
 1.25A 2vdvF-5h5zA:
undetectable		 2vdvF-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 PHE A 120
ASN A 134
PHE A  84
 None
 1.09A 2zbuD-5h5zA:
undetectable		 2zbuD-5h5zA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 PRO A 191
PHE A 275
LYS A 189
 None
 1.07A 3bjwG-5h5zA:
undetectable		 3bjwG-5h5zA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 ASP A 232
SER A 234
ARG A 178
 None
 0.91A 3loqA-5h5zA:
undetectable		 3loqA-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		4 / 8 TYR A 113
TRP A 144
TYR A 111
TRP A 130
 None
 1.50A 3wipD-5h5zA:
undetectable
3wipE-5h5zA:
undetectable		 3wipD-5h5zA:
undetectable
3wipE-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 TRP A 130
VAL A 138
TRP A 144
 None
 1.43A 3zq8A-5h5zA:
undetectable
3zq8B-5h5zA:
undetectable		 3zq8A-5h5zA:
undetectable
3zq8B-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 GLN A 108
THR A 107
THR A 106
 None
 0.75A 4fu9A-5h5zA:
undetectable		 4fu9A-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 GLN A 108
THR A 107
THR A 106
 None
 0.73A 4fufA-5h5zA:
undetectable		 4fufA-5h5zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 TYR A   8
TYR A  58
GLN A  62
 None
 1.11A 5jsdA-5h5zA:
undetectable
5jsdB-5h5zA:
undetectable		 5jsdA-5h5zA:
8.25
5jsdB-5h5zA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		3 / 3 TYR A   8
TYR A  58
GLN A  62
 None
 1.11A 5jsdB-5h5zA:
undetectable
5jsdC-5h5zA:
undetectable		 5jsdB-5h5zA:
8.25
5jsdC-5h5zA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		5 / 12 GLN A 152
TYR A  97
VAL A  65
GLY A  68
ALA A  69
 None
 1.07A 5jw1B-5h5zA:
undetectable		 5jw1B-5h5zA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h5z MHC CLASS I ANTIGEN
(Ctenopharyngodon
idella) 		5 / 12 GLN A 152
TYR A  97
VAL A  65
GLY A  68
ALA A  69
 None
 1.09A 5kirA-5h5zA:
undetectable		 5kirA-5h5zA:
9.26