SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h60'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 MET A 276
ASN A 256
GLN A  50
 None
None
UDP  A 401 (-4.6A)
 1.04A 1xoqB-5h60A:
undetectable		 1xoqB-5h60A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5h60 TRANSFERASE
(Escherichia
coli) 		4 / 5 PHE A 126
PHE A 202
SER A 217
PHE A  93
 None
 1.13A 2v0mD-5h60A:
undetectable		 2v0mD-5h60A:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 LEU A 273
MET A 193
MET A 254
 None
 1.06A 2vavF-5h60A:
undetectable		 2vavF-5h60A:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 5h60 TRANSFERASE
(Escherichia
coli) 		4 / 6 ILE A 259
PRO A 284
ASP A 130
ILE A 175
 None
 0.82A 3n3iA-5h60A:
undetectable		 3n3iA-5h60A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 TYR A 190
LEU A  47
ARG A 191
 None
 0.60A 3sufB-5h60A:
undetectable		 3sufB-5h60A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 5h60 TRANSFERASE
(Escherichia
coli) 		4 / 7 ASN A  68
ILE A  64
PHE A 106
PHE A  59
 None
 1.21A 3tvxB-5h60A:
undetectable		 3tvxB-5h60A:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 HIS A 316
GLY A 234
ILE A 235
 None
 0.61A 4k50A-5h60A:
undetectable		 4k50A-5h60A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 HIS A 316
GLY A 234
ILE A 235
 None
 0.59A 4k50I-5h60A:
undetectable		 4k50I-5h60A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 LYS A 162
ASN A 140
ASP A 166
 None
 0.84A 4o1eA-5h60A:
undetectable		 4o1eA-5h60A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5h60 TRANSFERASE
(Escherichia
coli) 		4 / 6 GLY A 240
PHE A 297
ILE A 293
PHE A 308
 None
 1.03A 4qogA-5h60A:
undetectable
4qogB-5h60A:
undetectable		 4qogA-5h60A:
19.82
4qogB-5h60A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5h60 TRANSFERASE
(Escherichia
coli) 		4 / 7 ILE A  78
LEU A  75
ILE A 119
ALA A 105
 None
 0.88A 6b5vC-5h60A:
undetectable
6b5vD-5h60A:
undetectable		 6b5vC-5h60A:
22.35
6b5vD-5h60A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5h60 TRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A  54
PHE A 187
GLY A 183
 None
 0.77A 6fgdA-5h60A:
undetectable		 6fgdA-5h60A:
undetectable