SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5h65 ADRENOCORTICAL
DYSPLASIA PROTEIN
HOMOLOG
PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 445
LEU B 274
ALA B 275
LEU A 466
LEU A 452
 None
 1.23A 1s9pB-5h65A:
undetectable		 1s9pB-5h65A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 5 ILE A 474
SER A 507
ARG A 510
LEU A 485
 None
 1.18A 1y0xX-5h65A:
undetectable		 1y0xX-5h65A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 LEU A 483
PRO A 491
ILE A 455
LEU A 454
 None
 1.11A 1ya4C-5h65A:
undetectable		 1ya4C-5h65A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 5 ILE A 624
MET A 587
LEU A 548
LEU A 603
 None
 1.11A 2zb7A-5h65A:
undetectable		 2zb7A-5h65A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.38A 4jksA-5h65A:
undetectable		 4jksA-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.38A 4jksB-5h65A:
undetectable		 4jksB-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.39A 4jkuA-5h65A:
undetectable		 4jkuA-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.40A 4k8kB-5h65A:
undetectable		 4k8kB-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.38A 4kalA-5h65A:
undetectable		 4kalA-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.38A 4kalB-5h65A:
undetectable		 4kalB-5h65A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5h65 PROTECTION OF
TELOMERES PROTEIN 1
(Homo
sapiens) 		4 / 4 SER A 421
LEU A 452
TYR A 419
PRO A 409
 None
 1.39A 4lcaA-5h65A:
undetectable		 4lcaA-5h65A:
21.77