SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		5 / 11 VAL A 607
ILE A 617
LEU A 621
LEU A 673
LEU A 542
 None
 1.23A 2a15A-5h69A:
undetectable		 2a15A-5h69A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 491
LEU A 493
GLU A 494
LEU A 679
 None
 0.75A 3h5gA-5h69A:
undetectable
3h5gC-5h69A:
undetectable		 3h5gA-5h69A:
7.28
3h5gC-5h69A:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		3 / 3 ALA A 479
ARG A 483
LYS A 487
 None
 0.76A 3kp3B-5h69A:
undetectable		 3kp3B-5h69A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		3 / 3 ALA A 479
ARG A 483
LYS A 487
 None
 0.77A 3kp5B-5h69A:
undetectable		 3kp5B-5h69A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		4 / 8 SER A 674
SER A 671
GLY A 544
GLY A 502
 None
 0.87A 4fo4B-5h69A:
undetectable		 4fo4B-5h69A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 621
ILE A 538
GLY A 543
VAL A 647
VAL A 653
 None
 1.16A 4nkvA-5h69A:
undetectable		 4nkvA-5h69A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A 549
ALA A 572
TYR A 500
LEU A 511
LEU A 672
 None
 1.41A 4qztC-5h69A:
undetectable		 4qztC-5h69A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A 550
TYR A 613
ALA A 616
 None
 0.51A 4ybnA-5h69A:
undetectable		 4ybnA-5h69A:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A 626
TYR A 534
ALA A 537
 None
 0.56A 4ybnA-5h69A:
undetectable		 4ybnA-5h69A:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5h69 CHROMOSOME PARTITION
PROTEIN SMC
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A 538
ALA A 541
ARG A 645
ALA A 545
LEU A 620
 None
 1.44A 4zo1X-5h69A:
undetectable		 4zo1X-5h69A:
22.79