SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5h6n PIERISIN-1
(Pieris
rapae) 		5 / 10 VAL A 113
VAL A 148
ILE A 177
PRO A  86
GLY A 171
 None
 1.43A 13gsA-5h6nA:
undetectable		 13gsA-5h6nA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5h6n PIERISIN-1
(Pieris
rapae) 		5 / 9 VAL A 113
VAL A 148
ILE A 177
PRO A  86
GLY A 171
 None
 1.43A 13gsB-5h6nA:
undetectable		 13gsB-5h6nA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 8 ALA A  15
PHE A 168
ALA A 144
LEU A  68
 None
 0.78A 2bxmA-5h6nA:
undetectable		 2bxmA-5h6nA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 4 VAL A  88
THR A  89
VAL A  17
GLY A 170
 None
 1.18A 2p2fB-5h6nA:
undetectable		 2p2fB-5h6nA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 4 LEU A  68
GLN A 165
THR A 115
THR A  56
 None
 1.49A 2zj0D-5h6nA:
undetectable		 2zj0D-5h6nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 8 GLN A 163
ASN A 107
TRP A 160
GLN A 165
 None
 1.35A 4d1yA-5h6nA:
undetectable
4d1yB-5h6nA:
undetectable		 4d1yA-5h6nA:
20.49
4d1yB-5h6nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 8 GLN A 165
GLN A 163
ASN A 107
TRP A 160
 None
 1.38A 4d1yA-5h6nA:
undetectable
4d1yB-5h6nA:
undetectable		 4d1yA-5h6nA:
20.49
4d1yB-5h6nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5h6n PIERISIN-1
(Pieris
rapae) 		5 / 12 PRO A  93
ALA A  14
ALA A  15
VAL A  17
GLY A 147
 None
 1.36A 5igpA-5h6nA:
undetectable		 5igpA-5h6nA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 5h6n PIERISIN-1
(Pieris
rapae) 		3 / 3 GLU A 141
ARG A 178
TYR A 143
 None
 0.61A 5trqB-5h6nA:
undetectable		 5trqB-5h6nA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 5h6n PIERISIN-1
(Pieris
rapae) 		4 / 6 ARG A  49
PHE A 112
PHE A 168
ILE A  12
 None
 1.13A 5vceA-5h6nA:
undetectable		 5vceA-5h6nA:
19.87