SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4001_1
(SERUM ALBUMIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 4 ARG A  90
LYS A  80
ASP A  92
GLY A  93
 None
 1.41A 1e7bB-5h6sA:
undetectable		 1e7bB-5h6sA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 7 LEU A 389
SER A 149
ASP A 147
PHE A 391
 None
 1.10A 1ismB-5h6sA:
undetectable		 1ismB-5h6sA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 5 ASP A  81
SER A  82
ASN A  97
SER A 136
 None
 1.23A 1kiaB-5h6sA:
undetectable		 1kiaB-5h6sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ASP A  81
SER A  82
ASN A  97
SER A 136
 None
 1.23A 1kiaC-5h6sA:
undetectable		 1kiaC-5h6sA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 8 GLY A 140
ILE A 330
SER A 332
GLU A 333
 None
 0.77A 1mrjA-5h6sA:
undetectable		 1mrjA-5h6sA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		6 / 10 ARG A 225
GLY A 157
ASP A  81
ILE A  79
GLY A 174
ILE A 180
 None
 1.11A 1sh9B-5h6sA:
undetectable		 1sh9B-5h6sA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.89A 1wmqA-5h6sA:
undetectable		 1wmqA-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.91A 1wmqB-5h6sA:
undetectable		 1wmqB-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.90A 1wpuA-5h6sA:
undetectable		 1wpuA-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.91A 1wpuB-5h6sA:
undetectable		 1wpuB-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 7 PHE A 234
PHE A 192
VAL A 430
MET A 371
 None
 1.06A 1wrlA-5h6sA:
undetectable
1wrlB-5h6sA:
undetectable		 1wrlA-5h6sA:
11.62
1wrlB-5h6sA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.91A 1wrqA-5h6sA:
undetectable		 1wrqA-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ARG A 444
ILE A 227
GLY A 443
ALA A 442
 None
 0.91A 1wrqB-5h6sA:
undetectable		 1wrqB-5h6sA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 LEU A 172
CYH A 187
ASP A 159
ALA A 160
ALA A 164
 None
 1.13A 2br4B-5h6sA:
undetectable		 2br4B-5h6sA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 7 ILE A 170
ARG A 235
MET A 237
THR A 238
 None
 1.19A 2zxwN-5h6sA:
undetectable
2zxwW-5h6sA:
undetectable		 2zxwN-5h6sA:
20.08
2zxwW-5h6sA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 5 ILE A 170
ARG A 235
MET A 237
THR A 238
 None
 1.15A 3abkN-5h6sA:
undetectable
3abkW-5h6sA:
undetectable		 3abkN-5h6sA:
20.08
3abkW-5h6sA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		6 / 12 ALA A 123
GLY A 174
SER A 155
GLY A 157
GLY A 158
LEU A 176
 None
None
HDH  A 600 (-3.3A)
None
None
HDH  A 600 (-4.2A)
 1.20A 3douA-5h6sA:
undetectable		 3douA-5h6sA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 4 GLU A 311
GLY A 314
THR A 315
GLU A 316
 None
 1.18A 3e9xA-5h6sA:
0.9		 3e9xA-5h6sA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A 173
SER A 156
SER A  78
ASP A 175
ARG A 181
 None
None
None
HDH  A 600 ( 4.9A)
None
 1.26A 3iv6D-5h6sA:
undetectable		 3iv6D-5h6sA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 LEU A 264
GLU A 267
PRO A 300
HIS A 266
 None
 1.32A 3ltwA-5h6sA:
undetectable		 3ltwA-5h6sA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 GLY A 443
ALA A 442
GLY A 431
VAL A 430
VAL A 294
 None
 0.98A 3oxwC-5h6sA:
undetectable		 3oxwC-5h6sA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A 157
GLY A 153
VAL A 135
ASN A 133
ALA A 123
 None
 0.96A 3p2kC-5h6sA:
undetectable		 3p2kC-5h6sA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 7 HIS A 434
GLU A 254
GLU A 436
PHE A 234
 None
 1.35A 3ql6A-5h6sA:
undetectable		 3ql6A-5h6sA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 6 ASP A 392
ALA A 141
LEU A 389
THR A 151
 None
 1.06A 3rozA-5h6sA:
undetectable		 3rozA-5h6sA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 ILE A 427
ILE A 284
ALA A 282
ASP A 281
LEU A 272
 None
 1.16A 3s79A-5h6sA:
undetectable		 3s79A-5h6sA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A  69
ILE A 170
GLY A 117
ALA A 115
ALA A 233
 None
 0.92A 3sudC-5h6sA:
undetectable		 3sudC-5h6sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 5 ILE A  13
PRO A  76
SER A  23
GLY A  74
 None
 1.18A 3tkdB-5h6sA:
undetectable		 3tkdB-5h6sA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 5 ILE A  13
PRO A  76
SER A  23
GLY A  74
 None
 1.15A 3tkdA-5h6sA:
undetectable		 3tkdA-5h6sA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 TYR A 190
GLY A 188
LEU A 423
GLY A 426
ALA A 456
 None
 0.97A 3vywC-5h6sA:
undetectable		 3vywC-5h6sA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 HIS A 336
SER A 155
GLY A 178
VAL A 182
VAL A 410
 None
HDH  A 600 (-3.3A)
HDH  A 600 (-4.3A)
None
None
 1.09A 4danA-5h6sA:
undetectable
4danB-5h6sA:
undetectable		 4danA-5h6sA:
22.59
4danB-5h6sA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLU A  30
VAL A  28
PRO A  76
THR A 169
SER A 226
 None
 1.39A 4k88A-5h6sA:
undetectable		 4k88A-5h6sA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 ILE A 427
ILE A 284
ALA A 282
ASP A 281
LEU A 272
 None
 1.12A 4kq8A-5h6sA:
undetectable		 4kq8A-5h6sA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A 157
ALA A 152
GLY A 154
GLY A 153
VAL A 135
 None
 0.82A 4o3fA-5h6sA:
undetectable		 4o3fA-5h6sA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		3 / 4 ARG A  16
GLY A  20
GLU A  19
 None
 0.58A 4z2dB-5h6sA:
1.4
4z2dC-5h6sA:
undetectable		 4z2dB-5h6sA:
23.18
4z2dC-5h6sA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		3 / 3 THR A 366
HIS A 266
LEU A 264
 None
 0.81A 5axdA-5h6sA:
undetectable		 5axdA-5h6sA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 9 SER A 134
THR A 151
ALA A 386
GLY A 158
ALA A 160
 None
 1.09A 5d0xK-5h6sA:
undetectable
5d0xL-5h6sA:
undetectable		 5d0xK-5h6sA:
20.62
5d0xL-5h6sA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A  74
GLY A 117
GLY A  70
VAL A  27
ILE A  13
 None
 1.01A 5ehiA-5h6sA:
undetectable		 5ehiA-5h6sA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A  74
GLY A 117
GLY A  70
VAL A  27
ILE A  13
 None
 1.01A 5eiwA-5h6sA:
undetectable		 5eiwA-5h6sA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 GLY A  74
GLY A 117
GLY A  70
VAL A  27
ILE A  13
 None
 1.00A 5ekxA-5h6sA:
undetectable		 5ekxA-5h6sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 ILE A 427
ILE A 284
ALA A 282
ASP A 281
LEU A 272
 None
 1.13A 5jkvA-5h6sA:
undetectable		 5jkvA-5h6sA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		6 / 12 GLY A 154
THR A 151
ILE A 180
GLY A 158
ALA A 160
ILE A 223
 None
 1.45A 5kb6A-5h6sA:
undetectable		 5kb6A-5h6sA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 LEU A 378
GLY A 426
PRO A 380
ALA A 379
PRO A 385
 None
 1.29A 5x6yC-5h6sA:
undetectable		 5x6yC-5h6sA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 7 VAL A 325
VAL A 321
ILE A 130
ASP A 127
 None
None
HDH  A 600 ( 4.0A)
None
 0.72A 5ywmX-5h6sA:
undetectable		 5ywmX-5h6sA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 12 HIS A  31
GLY A 117
GLY A  74
LEU A  77
PRO A 222
 None
 1.14A 6b3bA-5h6sA:
undetectable		 6b3bA-5h6sA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		4 / 4 GLY A 417
ARG A 181
ASN A 414
LEU A 418
 None
 1.28A 6b58A-5h6sA:
undetectable		 6b58A-5h6sA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		6 / 12 GLY A 124
ALA A 123
ASP A  81
ILE A  79
GLY A 173
VAL A 163
 None
 1.48A 6dj1B-5h6sA:
undetectable		 6dj1B-5h6sA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		6 / 12 GLY A 124
ALA A 123
ASP A  81
ILE A  79
GLY A 173
VAL A 163
 None
 1.48A 6dj2B-5h6sA:
undetectable		 6dj2B-5h6sA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 PRO A  76
LEU A  72
ASP A 105
ILE A 170
GLY A 171
 None
 1.43A 6dlzA-5h6sA:
undetectable
6dlzD-5h6sA:
2.5		 6dlzA-5h6sA:
8.94
6dlzD-5h6sA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 ILE A 170
GLY A 171
PRO A  76
LEU A  72
ASP A 105
 None
 1.43A 6dlzB-5h6sA:
2.0
6dlzC-5h6sA:
undetectable		 6dlzB-5h6sA:
8.94
6dlzC-5h6sA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 PRO A  76
LEU A  72
ASP A 105
ILE A 170
GLY A 171
 None
 1.44A 6dm1A-5h6sA:
undetectable
6dm1D-5h6sA:
2.5		 6dm1A-5h6sA:
8.94
6dm1D-5h6sA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5h6s AMIDASE
(Microbacterium
sp.
HM58-2) 		5 / 10 ILE A 170
GLY A 171
PRO A  76
LEU A  72
ASP A 105
 None
 1.43A 6dm1B-5h6sA:
2.4
6dm1C-5h6sA:
undetectable		 6dm1B-5h6sA:
8.94
6dm1C-5h6sA:
8.94