SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5h6y NUCLEOSOME-REMODELIN
G FACTOR SUBUNIT
BPTF
(Homo
sapiens) 		4 / 6 PRO A  92
VAL A  97
TYR A 105
ASN A 148
 None
 0.30A 5pbeA-5h6yA:
17.6		 5pbeA-5h6yA:
33.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5h6y NUCLEOSOME-REMODELIN
G FACTOR SUBUNIT
BPTF
(Homo
sapiens) 		3 / 3 GLU A  75
TYR A  74
ARG A 125
 None
 0.86A 5uunA-5h6yA:
2.1		 5uunA-5h6yA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5h6y NUCLEOSOME-REMODELIN
G FACTOR SUBUNIT
BPTF
(Homo
sapiens) 		3 / 3 GLU A  75
TYR A  74
ARG A 125
 None
 0.74A 5uunB-5h6yA:
undetectable		 5uunB-5h6yA:
18.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5h6y NUCLEOSOME-REMODELIN
G FACTOR SUBUNIT
BPTF
(Homo
sapiens) 		4 / 8 PRO A  92
VAL A  97
CYH A 144
TYR A 147
 None
 0.65A 5y1yA-5h6yA:
15.8		 5y1yA-5h6yA:
35.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5h6y NUCLEOSOME-REMODELIN
G FACTOR SUBUNIT
BPTF
(Homo
sapiens) 		4 / 8 VAL A  97
CYH A 144
TYR A 147
ASN A 148
 None
 0.38A 5y1yA-5h6yA:
15.8		 5y1yA-5h6yA:
35.20