SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 6 TRP A 270
TYR A 395
ILE A 385
TYR A 379
 BEM  A 502 ( 3.6A)
MAW  A 501 ( 4.5A)
None
None
 1.11A 1maaB-5h71A:
undetectable
1maaD-5h71A:
undetectable		 1maaB-5h71A:
20.50
1maaD-5h71A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 GLY A  84
GLY A  87
ASP A  78
ASP A  74
GLY A  73
 None
None
None
BEM  A 503 ( 3.7A)
None
 1.02A 1sqfA-5h71A:
undetectable		 1sqfA-5h71A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 TYR A 393
ASP A 392
ASP A 132
HIS A 110
 None
 1.14A 1t03A-5h71A:
undetectable		 1t03A-5h71A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		3 / 3 SER A 202
GLU A 305
ASP A 269
 None
 0.62A 2avdB-5h71A:
undetectable		 2avdB-5h71A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 LEU A 290
ARG A 142
ILE A 141
PHE A 266
GLY A 407
 None
 1.00A 2lbdA-5h71A:
undetectable		 2lbdA-5h71A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 LEU A  13
ILE A 319
LEU A  92
PRO A 128
ILE A 103
 None
 1.07A 2ygqA-5h71A:
undetectable		 2ygqA-5h71A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 11 HIS A 268
MET A 410
VAL A 417
ILE A 408
GLU A 305
 None
 1.13A 2yy8A-5h71A:
undetectable
2yy8B-5h71A:
undetectable		 2yy8A-5h71A:
16.02
2yy8B-5h71A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5h71 ALGQ2
(Sphingomonas
sp.) 		3 / 3 SER A  54
GLN A  55
PHE A  58
 None
 0.56A 3g4lC-5h71A:
undetectable		 3g4lC-5h71A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MYU_A_VIBA500_1
(HIGH AFFINITY
TRANSPORT SYSTEM
PROTEIN P37)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 10 ASN A  75
ASP A 206
TRP A 270
TYR A 129
ASP A 315
 BEM  A 503 ( 3.6A)
None
BEM  A 502 ( 3.6A)
BEM  A 502 ( 4.4A)
BEM  A 503 ( 4.9A)
 1.44A 3myuA-5h71A:
4.6		 3myuA-5h71A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 9 ILE A 319
VAL A  41
PHE A 333
ASP A  69
LEU A  13
 None
 1.16A 3ti1A-5h71A:
undetectable		 3ti1A-5h71A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 TRP A 390
ARG A 342
GLY A 341
PRO A 340
 None
 1.03A 3ucbB-5h71A:
undetectable		 3ucbB-5h71A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ASN A 196
GLU A 305
GLN A 310
TYR A 139
 None
 1.04A 3ugrA-5h71A:
undetectable		 3ugrA-5h71A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ASP A  74
ASP A  21
TRP A  23
SER A  54
 BEM  A 503 ( 3.7A)
None
None
None
 1.20A 4k7gB-5h71A:
undetectable		 4k7gB-5h71A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 ILE A 184
LEU A 164
LEU A 160
ILE A 141
THR A 274
 None
 0.94A 4m2xC-5h71A:
undetectable		 4m2xC-5h71A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 11 ASP A 343
PRO A  30
ALA A  32
SER A 345
GLY A 382
 None
 1.13A 4mmaA-5h71A:
undetectable		 4mmaA-5h71A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 5 TYR A 129
GLN A 391
ASP A 206
ASP A 189
 BEM  A 502 ( 4.4A)
MAW  A 501 ( 3.7A)
None
None
 1.47A 4qtuB-5h71A:
undetectable		 4qtuB-5h71A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 GLU A 190
ASP A 185
ARG A 193
SER A 273
THR A 267
 None
None
None
MAW  A 501 ( 2.5A)
None
 1.08A 4uroD-5h71A:
undetectable		 4uroD-5h71A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A  20
ARG A 255
ASP A 269
TYR A 379
 BEM  A 502 ( 4.2A)
MAW  A 501 ( 4.8A)
None
None
 1.40A 5a06A-5h71A:
undetectable		 5a06A-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A 250
ASP A 244
ILE A 247
TYR A 238
 None
 1.00A 5a06B-5h71A:
undetectable		 5a06B-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A  20
ARG A 255
ASP A 269
TYR A 379
 BEM  A 502 ( 4.2A)
MAW  A 501 ( 4.8A)
None
None
 1.40A 5a06C-5h71A:
undetectable		 5a06C-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A  20
ARG A 255
ASP A 269
TYR A 379
 BEM  A 502 ( 4.2A)
MAW  A 501 ( 4.8A)
None
None
 1.39A 5a06D-5h71A:
undetectable		 5a06D-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A  20
ARG A 255
ASP A 269
TYR A 379
 BEM  A 502 ( 4.2A)
MAW  A 501 ( 4.8A)
None
None
 1.40A 5a06E-5h71A:
undetectable		 5a06E-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 7 ARG A  20
ARG A 255
ASP A 269
TYR A 379
 BEM  A 502 ( 4.2A)
MAW  A 501 ( 4.8A)
None
None
 1.36A 5a06F-5h71A:
undetectable		 5a06F-5h71A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 ASP A 185
THR A 267
PHE A 266
PRO A 172
VAL A 234
 None
 1.35A 5dlvB-5h71A:
undetectable		 5dlvB-5h71A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 ILE A 141
GLU A 143
ASN A 156
THR A 162
LEU A 151
 None
 1.22A 5fhzD-5h71A:
undetectable		 5fhzD-5h71A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5h71 ALGQ2
(Sphingomonas
sp.) 		3 / 3 ARG A 193
HIS A 187
ARG A 137
 None
BEM  A 503 ( 3.9A)
BEM  A 502 ( 3.7A)
 1.06A 5iaoC-5h71A:
undetectable		 5iaoC-5h71A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5h71 ALGQ2
(Sphingomonas
sp.) 		3 / 3 ARG A 193
HIS A 187
ARG A 137
 None
BEM  A 503 ( 3.9A)
BEM  A 502 ( 3.7A)
 1.06A 5iaoF-5h71A:
undetectable		 5iaoF-5h71A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 12 LEU A  92
ILE A 127
GLY A 316
VAL A 113
ILE A 117
 None
 0.94A 5ycnA-5h71A:
undetectable		 5ycnA-5h71A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 4 GLY A 260
ARG A 142
ASN A 262
LEU A 281
 None
 1.15A 6b58A-5h71A:
undetectable		 6b58A-5h71A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5h71 ALGQ2
(Sphingomonas
sp.) 		5 / 10 ALA A  88
TYR A 125
GLU A 114
PHE A 333
VAL A  71
 None
 1.39A 6b89A-5h71A:
undetectable		 6b89A-5h71A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5h71 ALGQ2
(Sphingomonas
sp.) 		4 / 5 TYR A 393
GLN A 391
GLY A 138
ILE A 408
 None
MAW  A 501 ( 3.7A)
None
None
 1.41A 6debB-5h71A:
undetectable		 6debB-5h71A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5h71 ALGQ2
(Sphingomonas
sp.) 		3 / 3 ILE A 319
THR A 320
PRO A 326
 None
 0.61A 6ncsA-5h71A:
undetectable		 6ncsA-5h71A:
19.72