SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 4 HIS A 288
LEU A 431
LEU A 350
LEU A 136
 None
 1.21A 1a4lD-5h7dA:
undetectable		 1a4lD-5h7dA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 GLY A 305
GLY A  97
LEU A  76
ASP A  86
 None
 0.84A 1aegA-5h7dA:
undetectable		 1aegA-5h7dA:
21.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 11 PHE E 164
ILE E 172
LEU E 177
MET E 181
LEU E 184
 None
 0.77A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 11 PHE E 164
ILE E 172
MET E 181
LEU E 184
MET E 196
 None
 0.81A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 11 PHE E 164
MET E 181
LEU E 184
MET E 196
VAL E 200
 None
 0.88A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		4 / 8 MET E 181
GLN E 186
PRO E 188
GLU E 192
 None
 0.66A 1dtlA-5h7dE:
8.3		 1dtlA-5h7dE:
40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 GLY A 369
PHE A 395
VAL A 381
MET A 408
ALA A 448
 None
 1.00A 1e3vA-5h7dA:
undetectable		 1e3vA-5h7dA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 PHE A 284
GLY A 278
ARG A 279
LEU A 431
 None
 0.77A 1gsfC-5h7dA:
undetectable		 1gsfC-5h7dA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 THR A 137
PRO A 138
GLY A 139
THR A 315
 None
 0.76A 1h4oB-5h7dA:
undetectable		 1h4oB-5h7dA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 THR A 137
PRO A 138
GLY A 139
THR A 315
 None
 0.77A 1oc3A-5h7dA:
undetectable		 1oc3A-5h7dA:
18.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 10 MET E 181
GLN E 186
GLU E 192
MET E 196
MET E 216
 None
 0.79A 1wrkA-5h7dE:
8.7
1wrkB-5h7dE:
8.6		 1wrkA-5h7dE:
40.68
1wrkB-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 10 MET E 181
LEU E 184
GLN E 186
MET E 196
MET E 216
 None
 0.82A 1wrkA-5h7dE:
8.7
1wrkB-5h7dE:
8.6		 1wrkA-5h7dE:
40.68
1wrkB-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 9 MET E 181
GLN E 186
GLU E 192
MET E 196
MET E 216
 None
 0.77A 1wrlC-5h7dE:
8.6
1wrlD-5h7dE:
8.5		 1wrlC-5h7dE:
40.68
1wrlD-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		4 / 5 PHE E 164
LEU E 184
PHE E 213
MET E 217
 None
 1.23A 1wrlC-5h7dE:
8.6		 1wrlC-5h7dE:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_E_TFPE210_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 9 MET E 181
GLN E 186
GLU E 192
MET E 196
MET E 216
 None
 0.81A 1wrlE-5h7dE:
8.8
1wrlF-5h7dE:
8.7		 1wrlE-5h7dE:
40.68
1wrlF-5h7dE:
40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 LEU A 351
ASN A 348
LEU A 344
ALA A 345
LEU A 302
 None
 1.40A 1ya3A-5h7dA:
undetectable		 1ya3A-5h7dA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 LEU A 351
ASN A 348
LEU A 344
ALA A 345
LEU A 302
 None
 1.40A 2aa5B-5h7dA:
undetectable		 2aa5B-5h7dA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 8 ARG A 446
ALA A 445
LEU A 380
VAL A 381
 None
 0.72A 2bxgA-5h7dA:
undetectable		 2bxgA-5h7dA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 7 THR A 137
PRO A 138
GLY A 139
THR A 315
 None
 0.74A 2vl2B-5h7dA:
undetectable		 2vl2B-5h7dA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 PRO A 356
ALA A 357
ALA A 345
ALA A 343
MET A 283
 None
 1.27A 2x2nA-5h7dA:
undetectable		 2x2nA-5h7dA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 10 VAL A 246
ILE A 240
LEU A 431
GLY A 281
ALA A 359
 None
 1.12A 2xf3A-5h7dA:
undetectable		 2xf3A-5h7dA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 9 VAL A 246
ILE A 240
LEU A 431
GLY A 281
ALA A 359
 None
 1.12A 2xf3B-5h7dA:
undetectable		 2xf3B-5h7dA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 9 VAL A 246
ILE A 240
LEU A 431
GLY A 281
ALA A 359
 None
 1.12A 2xfsB-5h7dA:
undetectable		 2xfsB-5h7dA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 9 VAL A 246
ILE A 240
LEU A 431
GLY A 281
ALA A 359
 None
 1.15A 2xh9B-5h7dA:
undetectable		 2xh9B-5h7dA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 GLY A 304
VAL A  96
MET A 277
LEU A 298
ILE A 347
 None
 1.32A 3h52A-5h7dA:
undetectable		 3h52A-5h7dA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 7 PHE A 180
PHE A 196
PHE A  91
LYS A 183
 None
 1.19A 3hggA-5h7dA:
undetectable		 3hggA-5h7dA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 VAL A  96
GLY A  97
LEU A  73
LEU A 302
ILE A 309
 None
 1.13A 3ijdB-5h7dA:
undetectable		 3ijdB-5h7dA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
ZPA963,CALMODULIN
(Caenorhabditis
elegans;
Escherichia
coli;
Staphylococcus
aureus;
synthetic
construct) 		5 / 10 THR E 109
PHE A 458
GLU E 111
LEU E 134
ILE E 131
 None
 1.15A 3kvrA-5h7dE:
undetectable		 3kvrA-5h7dE:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 11 GLY A 150
VAL A 154
GLU A 155
SER A 149
VAL A 273
 None
 1.25A 4danA-5h7dA:
undetectable		 4danA-5h7dA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 10 GLY A  61
GLY A  60
ASN A  35
VAL A  66
PHE A 409
 None
 1.25A 4fgkA-5h7dA:
undetectable
4fgkB-5h7dA:
undetectable		 4fgkA-5h7dA:
20.12
4fgkB-5h7dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		3 / 3 GLN A 119
THR A 332
THR A 331
 None
 0.82A 4fu9A-5h7dA:
undetectable		 4fu9A-5h7dA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 7 PHE A 370
LEU A 373
ALA A 448
MET A 408
 None
 1.02A 4rjdB-5h7dA:
undetectable		 4rjdB-5h7dA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 GLY A  92
GLY A 305
ASN A 100
SER A  72
GLN A 437
 None
 1.03A 4rtmA-5h7dA:
2.1		 4rtmA-5h7dA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 12 GLY A 303
GLY A 305
GLY A  97
ALA A 339
LEU A 302
 None
 1.17A 5c0oE-5h7dA:
undetectable		 5c0oE-5h7dA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 4 LEU A 298
ILE A 313
PRO A 138
LEU A 136
 None
 1.11A 5eb3A-5h7dA:
3.8		 5eb3A-5h7dA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 6 ALA A 345
THR A 346
VAL A 349
VAL A 306
 None
 0.88A 5eckA-5h7dA:
undetectable		 5eckA-5h7dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 6 ALA A 345
THR A 346
VAL A 349
VAL A 306
 None
 0.95A 5eckD-5h7dA:
1.6		 5eckD-5h7dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 6 ALA A 345
THR A 346
VAL A 349
VAL A 306
 None
 0.90A 5eclD-5h7dA:
undetectable		 5eclD-5h7dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 7 ALA A 345
THR A 346
VAL A 349
VAL A 306
 None
 0.72A 5ecoD-5h7dA:
undetectable		 5ecoD-5h7dA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 11 ILE A 442
LEU A 367
PHE A 370
LEU A 373
ALA A 374
 None
 1.18A 5ji0A-5h7dA:
undetectable		 5ji0A-5h7dA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 10 ALA A 311
ALA A 301
GLY A 303
ALA A 343
THR A 346
 None
 1.00A 5lf3V-5h7dA:
undetectable
5lf3W-5h7dA:
undetectable		 5lf3V-5h7dA:
18.76
5lf3W-5h7dA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 11 ALA A 311
ALA A 301
GLY A 303
ALA A 343
THR A 346
 None
 1.01A 5lf7H-5h7dA:
undetectable
5lf7I-5h7dA:
undetectable		 5lf7H-5h7dA:
18.76
5lf7I-5h7dA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 11 ALA A 311
ALA A 301
GLY A 303
ALA A 343
THR A 346
 None
 0.99A 5lf7V-5h7dA:
undetectable
5lf7W-5h7dA:
undetectable		 5lf7V-5h7dA:
18.76
5lf7W-5h7dA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		5 / 10 MET A 283
PHE A 284
ILE A 309
ALA A 299
LEU A 298
 None
 1.37A 5oy0b-5h7dA:
undetectable		 5oy0b-5h7dA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 5h7d ZPA963,CALMODULIN
(Caenorhabditis
elegans;
synthetic
construct) 		5 / 10 LEU E 177
MET E 196
GLU E 199
VAL E 200
ILE E 208
 None
 0.91A 5v02B-5h7dE:
undetectable
5v02R-5h7dE:
9.2		 5v02B-5h7dE:
17.50
5v02R-5h7dE:
58.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5h7d PUTRESCINE
AMINOTRANSFERASE,IMM
UNOGLOBULIN
G-BINDING PROTEIN A
(Escherichia
coli;
Staphylococcus
aureus) 		4 / 5 ARG A 375
ALA A 374
GLN A 372
ILE A 442
 None
 1.09A 6f6sA-5h7dA:
undetectable
6f6sB-5h7dA:
undetectable		 6f6sA-5h7dA:
10.71
6f6sB-5h7dA:
12.65