SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Deinococcus
radiodurans) 		5 / 12 ILE A 146
VAL A  90
LEU A 190
TYR A  44
PHE A 208
 None
 1.47A 2no0A-5h7eA:
undetectable		 2no0A-5h7eA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Deinococcus
radiodurans) 		5 / 12 ILE A 146
VAL A  90
LEU A 190
TYR A  44
PHE A 208
 None
 1.49A 2no0B-5h7eA:
undetectable		 2no0B-5h7eA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Deinococcus
radiodurans) 		4 / 4 TRP A 183
LEU A 111
LEU A  56
THR A  53
 None
 1.45A 4bboD-5h7eA:
undetectable		 4bboD-5h7eA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Deinococcus
radiodurans) 		3 / 3 ARG A  71
ASP A  73
TYR A 202
 None
None
GOL  A 301 (-4.7A)
 0.94A 4yo9B-5h7eA:
undetectable		 4yo9B-5h7eA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 5h7e RNA 2',3'-CYCLIC
PHOSPHODIESTERASE
(Deinococcus
radiodurans) 		5 / 12 ALA A 144
ILE A 151
GLY A 150
LEU A 142
LEU A 100
 None
 1.25A 5nfjC-5h7eA:
undetectable		 5nfjC-5h7eA:
23.39