SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 7 SER A 107
TYR A 110
ASN A 109
TYR A 112
 None
 0.89A 1dssG-5h7tA:
undetectable		 1dssG-5h7tA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 SER A 107
TYR A 110
ASN A 109
TYR A 112
 None
 0.87A 1dssR-5h7tA:
undetectable		 1dssR-5h7tA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 7 PHE A  43
SER A  32
PHE A  11
LEU A 195
 None
 0.86A 1qcaA-5h7tA:
undetectable		 1qcaA-5h7tA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 ASN A  62
PHE A 161
SER A 183
ALA A  58
 None
 1.17A 1rqpC-5h7tA:
undetectable		 1rqpC-5h7tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 ASN A  62
PHE A 161
SER A 183
ALA A  58
 None
 1.13A 1rqpA-5h7tA:
undetectable		 1rqpA-5h7tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 ASN A  62
PHE A 161
SER A 183
ALA A  58
 None
 1.10A 2v7uA-5h7tA:
undetectable		 2v7uA-5h7tA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 SER A 107
TYR A 110
ASN A 109
TYR A 112
 None
 0.86A 3dmtC-5h7tA:
undetectable		 3dmtC-5h7tA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 PHE A 161
ILE A 168
ALA A  64
THR A  67
 None
 0.90A 3me6B-5h7tA:
undetectable		 3me6B-5h7tA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		5 / 11 THR A 140
ALA A 141
PHE A  59
PHE A  27
ILE A  73
 None
 1.15A 4claA-5h7tA:
undetectable		 4claA-5h7tA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 8 LEU A 124
GLY A 113
ALA A 114
SER A 117
 None
 0.63A 5f1aA-5h7tA:
undetectable		 5f1aA-5h7tA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 7 LEU A 124
GLY A 113
ALA A 114
SER A 117
 None
 0.55A 5f1aB-5h7tA:
undetectable		 5f1aB-5h7tA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		4 / 7 PHE A  70
ALA A  19
GLY A  24
GLY A  26
 None
 0.67A 5ybbB-5h7tA:
undetectable		 5ybbB-5h7tA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 5h7t CLASS IV CHITINASE
(Cryptomeria
japonica) 		5 / 12 PHE A  59
ILE A  56
VAL A   6
PHE A  11
VAL A 142
 None
 1.22A 6ap6A-5h7tA:
undetectable		 6ap6A-5h7tA:
21.68