SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 VAL A  76
VAL A  78
TRP A 149
 None
 0.86A 1av2C-5h83A:
undetectable
1av2D-5h83A:
undetectable		 1av2C-5h83A:
6.02
1av2D-5h83A:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 PHE A  26
THR A  50
ALA A 333
ILE A 337
ALA A  19
 None
 1.22A 1vq1A-5h83A:
4.7		 1vq1A-5h83A:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 VAL A  76
VAL A  78
TRP A 149
 None
 0.84A 1w5uC-5h83A:
undetectable
1w5uD-5h83A:
undetectable		 1w5uC-5h83A:
6.02
1w5uD-5h83A:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 VAL A  78
TRP A 149
VAL A  76
 None
 0.92A 2izqA-5h83A:
undetectable
2izqB-5h83A:
undetectable		 2izqA-5h83A:
6.02
2izqB-5h83A:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 LEU A 192
ILE A 248
ILE A 166
SER A 170
ALA A 164
 None
 1.20A 3axtA-5h83A:
5.1		 3axtA-5h83A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 VAL A  76
VAL A  78
TRP A 149
 None
 0.81A 3l8lC-5h83A:
undetectable
3l8lD-5h83A:
undetectable		 3l8lC-5h83A:
6.02
3l8lD-5h83A:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 4 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.16A 3w9tA-5h83A:
0.0		 3w9tA-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.17A 3w9tA-5h83A:
undetectable		 3w9tA-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.23A 3w9tB-5h83A:
undetectable		 3w9tB-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB507_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 4 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.16A 3w9tB-5h83A:
0.0		 3w9tB-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.17A 3w9tC-5h83A:
undetectable		 3w9tC-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 ASP A  54
GLY A  72
TYR A  53
 None
 0.79A 3w9tC-5h83A:
undetectable		 3w9tC-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.29A 3w9tD-5h83A:
undetectable		 3w9tD-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.16A 3w9tD-5h83A:
undetectable		 3w9tD-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.18A 3w9tD-5h83A:
undetectable		 3w9tD-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE503_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 4 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.16A 3w9tE-5h83A:
0.0		 3w9tE-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.34A 3w9tE-5h83A:
undetectable		 3w9tE-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF502_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 4 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.17A 3w9tF-5h83A:
0.0		 3w9tF-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.17A 3w9tG-5h83A:
undetectable		 3w9tG-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 ASP A  54
GLY A  72
TYR A  53
 None
 0.79A 3w9tG-5h83A:
undetectable		 3w9tG-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 ASP A  54
GLU A  74
GLY A  72
TYR A  53
 None
ZN  A 901 (-2.9A)
None
None
 1.37A 3w9tG-5h83A:
undetectable		 3w9tG-5h83A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 THR A 167
ILE A 166
GLU A 305
PHE A 100
 None
 1.11A 4ac9C-5h83A:
3.2		 4ac9C-5h83A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 THR A 167
ILE A 166
GLU A 305
PHE A 100
 None
 1.15A 4acaC-5h83A:
3.2		 4acaC-5h83A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 5 THR A 167
ILE A 166
GLU A 305
PHE A 100
 None
 1.16A 4acbC-5h83A:
3.4		 4acbC-5h83A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		3 / 3 SER A 257
ALA A 255
VAL A 254
 None
 0.53A 4o2bA-5h83A:
undetectable		 4o2bA-5h83A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		4 / 8 ILE A 327
PRO A  28
LEU A 354
PHE A  31
 None
 0.83A 4qopC-5h83A:
undetectable		 4qopC-5h83A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 ARG A  33
VAL A  95
PHE A  43
VAL A 350
GLY A  72
 None
 1.15A 5i8fA-5h83A:
undetectable		 5i8fA-5h83A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 VAL A 322
ASP A 321
HIS A 156
LEU A 155
ARG A 198
 None
 1.16A 5m5cB-5h83A:
undetectable		 5m5cB-5h83A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 ILE A 310
LEU A 161
VAL A 147
GLY A  96
GLY A  98
 None
 1.08A 5nnaA-5h83A:
undetectable		 5nnaA-5h83A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 ILE A 310
LEU A 161
VAL A 147
GLY A  96
GLY A  98
 None
 1.09A 5nnaB-5h83A:
undetectable		 5nnaB-5h83A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 ILE A 310
LEU A 161
VAL A 147
GLY A  96
GLY A  98
 None
 1.07A 5nnaC-5h83A:
undetectable		 5nnaC-5h83A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 ILE A 310
LEU A 161
VAL A 147
GLY A  96
GLY A  98
 None
 1.07A 5nnaD-5h83A:
undetectable		 5nnaD-5h83A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 PHE A 224
GLY A 190
GLY A 193
ILE A 197
LEU A 221
 None
 1.21A 5ul4A-5h83A:
5.2		 5ul4A-5h83A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 HIS A 127
ASP A  54
GLY A  99
HIS A  73
PHE A  69
 None
None
None
ZN  A 901 (-3.1A)
None
 1.33A 6exiA-5h83A:
6.6		 6exiA-5h83A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 5h83 HETEROYOHIMBINE
SYNTHASE HYS
(Catharanthus
roseus) 		5 / 12 HIS A 127
ASP A  54
GLY A  99
HIS A  73
PHE A  69
 None
None
None
ZN  A 901 (-3.1A)
None
 1.28A 6exiD-5h83A:
8.2		 6exiD-5h83A:
10.03