SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A  75
VAL A  77
TRP A 115
 None
 0.97A 1gmkA-5h98A:
undetectable
1gmkB-5h98A:
undetectable		 1gmkA-5h98A:
9.24
1gmkB-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.75A 1jnoA-5h98A:
undetectable		 1jnoA-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.75A 1jnoB-5h98A:
undetectable		 1jnoB-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.81A 1jo3A-5h98A:
undetectable		 1jo3A-5h98A:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.81A 1jo3B-5h98A:
undetectable		 1jo3B-5h98A:
6.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.87A 1jo4A-5h98A:
undetectable		 1jo4A-5h98A:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.88A 1jo4B-5h98A:
undetectable		 1jo4B-5h98A:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.82A 1magA-5h98A:
undetectable		 1magA-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.82A 1magB-5h98A:
undetectable		 1magB-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.77A 1ng8A-5h98A:
undetectable		 1ng8A-5h98A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.77A 1ng8B-5h98A:
undetectable		 1ng8B-5h98A:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.86A 1nrmA-5h98A:
undetectable		 1nrmA-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.85A 1nrmB-5h98A:
undetectable		 1nrmB-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.80A 1nruA-5h98A:
undetectable		 1nruA-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.80A 1nruB-5h98A:
undetectable		 1nruB-5h98A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.84A 1nt6A-5h98A:
undetectable		 1nt6A-5h98A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 135
VAL A  69
TRP A 115
 None
 0.84A 1nt6B-5h98A:
undetectable		 1nt6B-5h98A:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A  65
VAL A  69
TRP A 115
 None
 1.01A 1tkqA-5h98A:
undetectable		 1tkqA-5h98A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ALA A 188
VAL A 186
TRP A 222
 None
 0.93A 1tkqA-5h98A:
undetectable		 1tkqA-5h98A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		5 / 10 GLY A 185
VAL A  55
GLY A  56
MET A  57
VAL A 183
 None
 1.13A 1v3qE-5h98A:
undetectable		 1v3qE-5h98A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		4 / 5 ARG A  35
LEU A  32
PRO A 139
ASP A   9
 None
 1.09A 3ufnA-5h98A:
undetectable
3ufnB-5h98A:
undetectable		 3ufnA-5h98A:
18.41
3ufnB-5h98A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		5 / 8 GLY A  56
PHE A  71
SER A 110
ASN A 136
HIS A 210
 None
 0.79A 4wryA-5h98A:
10.4		 4wryA-5h98A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		4 / 8 GLY A  56
PHE A  71
SER A 110
ASN A 136
 None
 0.68A 4wrzA-5h98A:
10.3		 4wrzA-5h98A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		4 / 8 GLY A  56
PHE A  71
SER A 110
HIS A 210
 None
 0.72A 4wrzA-5h98A:
10.3		 4wrzA-5h98A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		4 / 8 GLY A  56
PHE A  71
SER A 110
ASN A 136
 None
 0.72A 4ws1A-5h98A:
9.8		 4ws1A-5h98A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		4 / 8 GLY A  56
PHE A  71
SER A 110
HIS A 210
 None
 0.71A 4ws1A-5h98A:
9.8		 4ws1A-5h98A:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5h98 GEOBACTER
METALLIREDUCENS
SMUG1
(Geobacter
metallireducens) 		3 / 3 ARG A 131
PHE A 133
PHE A 237
 None
 0.93A 6nknC-5h98A:
undetectable
6nknJ-5h98A:
undetectable		 6nknC-5h98A:
21.07
6nknJ-5h98A:
13.70