SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 8 PHE A 126
ASN A 127
GLU A 133
GLY A 132
 None
 1.09A 1ykiA-5h9kA:
undetectable
1ykiB-5h9kA:
undetectable		 1ykiA-5h9kA:
20.28
1ykiB-5h9kA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 8 PHE A 126
ASN A 127
GLU A 133
GLY A 132
 None
 1.09A 1ykiA-5h9kA:
undetectable
1ykiB-5h9kA:
undetectable		 1ykiA-5h9kA:
20.28
1ykiB-5h9kA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 8 PHE A 126
ASN A 127
GLU A 133
GLY A 132
 None
 1.08A 1ykiC-5h9kA:
undetectable
1ykiD-5h9kA:
undetectable		 1ykiC-5h9kA:
20.28
1ykiD-5h9kA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		3 / 3 GLY A  60
GLU A  46
ASN A  62
 None
 0.50A 1zq9A-5h9kA:
undetectable		 1zq9A-5h9kA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 6 LEU A 108
LEU A 124
SER A  36
THR A  34
 None
 0.95A 4d7bB-5h9kA:
undetectable		 4d7bB-5h9kA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		5 / 12 ALA A  96
TYR A  94
PHE A  81
THR A  92
ASN A  57
 None
 1.48A 4z7fA-5h9kA:
undetectable		 4z7fA-5h9kA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 7 LEU A 108
LEU A 124
SER A  36
THR A  34
 None
 0.96A 5bojB-5h9kA:
undetectable		 5bojB-5h9kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		4 / 6 LEU A 108
LEU A 124
SER A  36
THR A  34
 None
 0.96A 5l4iB-5h9kA:
undetectable		 5l4iB-5h9kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 5h9k LIPOCALIN AI-4
(Rhodnius
prolixus) 		3 / 3 THR A 148
GLU A  99
ASN A 143
 None
 0.55A 6nj9K-5h9kA:
undetectable		 6nj9K-5h9kA:
17.42