SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h9v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 5h9v RIBONUCLEASE ZC3H12A
(Mus
musculus) 		4 / 5 ARG A 183
ASP A 141
ASP A 225
ASP A 226
 None
 1.49A 3naiC-5h9vA:
undetectable		 3naiC-5h9vA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5h9v RIBONUCLEASE ZC3H12A
(Mus
musculus) 		5 / 12 VAL A 139
ASP A 226
ALA A 233
SER A 236
PHE A 259
 None
 1.26A 5hnzB-5h9vA:
undetectable		 5hnzB-5h9vA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 5h9v RIBONUCLEASE ZC3H12A
(Mus
musculus) 		4 / 8 LEU A 288
HIS A 172
VAL A 239
LEU A 265
 None
 0.85A 6cb4A-5h9vA:
undetectable		 6cb4A-5h9vA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5h9v RIBONUCLEASE ZC3H12A
(Mus
musculus) 		5 / 12 VAL A 139
VAL A 240
SER A 236
PHE A 259
TYR A 246
 None
 1.36A 6h7mB-5h9vA:
undetectable		 6h7mB-5h9vA:
15.09