SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5h9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		4 / 5 TYR A 371
VAL A 357
VAL A 400
ASP A 398
 None
 1.33A 1dz6B-5h9xA:
undetectable		 1dz6B-5h9xA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 11 LEU A 262
TYR A 244
ALA A 404
GLY A 402
TYR A 406
 None
 1.35A 1l5rA-5h9xA:
undetectable		 1l5rA-5h9xA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 THR A 359
PRO A 361
SER A 330
TYR A 329
LEU A 353
 None
 1.22A 1z9hA-5h9xA:
undetectable		 1z9hA-5h9xA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 THR A 359
PRO A 361
SER A 330
TYR A 329
LEU A 353
 None
 1.22A 1z9hB-5h9xA:
undetectable		 1z9hB-5h9xA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 THR A 359
PRO A 361
SER A 330
TYR A 329
LEU A 353
 None
 1.23A 1z9hC-5h9xA:
undetectable		 1z9hC-5h9xA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 THR A 359
PRO A 361
SER A 330
TYR A 329
LEU A 353
 None
 1.21A 1z9hD-5h9xA:
undetectable		 1z9hD-5h9xA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 10 ILE A 416
ILE A  98
GLY A 420
PHE A 256
VAL A 235
 None
 1.25A 3elzB-5h9xA:
undetectable		 3elzB-5h9xA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 LEU A 407
ILE A 131
LEU A 198
VAL A 235
LEU A 415
 None
 1.09A 3gwxB-5h9xA:
undetectable		 3gwxB-5h9xA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 HIS A 384
GLY A 390
GLY A 402
ALA A 351
CYH A 350
 None
 0.99A 3sufD-5h9xA:
undetectable		 3sufD-5h9xA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		3 / 3 ARG A 197
TYR A 207
ASN A 162
 None
 0.97A 4ffwB-5h9xA:
undetectable		 4ffwB-5h9xA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 PHE A  68
TYR A  31
VAL A  33
ALA A  62
ALA A   7
 None
 1.30A 4fiaA-5h9xA:
undetectable		 4fiaA-5h9xA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 PHE A  68
TYR A  31
VAL A  33
ALA A  62
ALA A   7
 None
 1.30A 4fiaA-5h9xA:
undetectable		 4fiaA-5h9xA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 9 GLU A 111
GLY A 113
VAL A 114
PRO A 191
GLY A 152
 None
 1.50A 4fimA-5h9xA:
undetectable		 4fimA-5h9xA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		4 / 5 PHE A 326
TYR A 325
PHE A 316
ILE A 337
 None
 1.26A 4jx1E-5h9xA:
undetectable		 4jx1E-5h9xA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		3 / 3 ARG A 281
TRP A 421
ILE A 231
 None
 1.03A 4mwxA-5h9xA:
undetectable		 4mwxA-5h9xA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 11 ARG A 261
ILE A  98
ILE A 258
VAL A 263
LEU A 407
 None
 1.34A 5jkwA-5h9xA:
undetectable		 5jkwA-5h9xA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		3 / 3 LYS A 181
TRP A 133
SER A 183
 None
 0.99A 5nwwA-5h9xA:
undetectable		 5nwwA-5h9xA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 LEU A 200
ILE A 182
HIS A 260
LEU A 262
TYR A 244
 None
 1.23A 5ycpA-5h9xA:
undetectable		 5ycpA-5h9xA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		4 / 7 ILE A 182
VAL A 235
LEU A 200
LEU A 415
 None
 0.65A 6g9bA-5h9xA:
undetectable
6g9bB-5h9xA:
undetectable		 6g9bA-5h9xA:
11.90
6g9bB-5h9xA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		3 / 3 ASP A 225
ASP A 252
ASN A 247
 None
 0.77A 6gngB-5h9xA:
undetectable		 6gngB-5h9xA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 5h9x BETA-1,3-GLUCANASE
(Paenibacillus
barengoltzii) 		5 / 12 LEU A 190
ILE A 193
TRP A 145
PHE A 237
ILE A 136
 None
 1.45A 6qyaB-5h9xA:
undetectable		 6qyaB-5h9xA:
20.48