SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ha8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		3 / 3 SER A 108
GLN A 107
PHE A 110
 None
 0.84A 3g4lC-5ha8A:
undetectable		 3g4lC-5ha8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		5 / 12 VAL A 129
ALA A 132
VAL A 112
GLY A 105
THR A 127
 None
 1.33A 4mm6A-5ha8A:
undetectable		 4mm6A-5ha8A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		5 / 12 HIS A 100
VAL A 102
LEU A 178
VAL A  44
PRO A  45
 None
 1.13A 4xiwB-5ha8A:
undetectable
4xiwE-5ha8A:
undetectable		 4xiwB-5ha8A:
22.54
4xiwE-5ha8A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		4 / 6 PHE A 168
GLY A 123
TYR A 163
ALA A 121
 None
 1.25A 4yshB-5ha8A:
undetectable		 4yshB-5ha8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		3 / 3 GLN A 107
THR A 135
ASP A 109
 None
 0.93A 5k9dA-5ha8A:
undetectable		 5k9dA-5ha8A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ha8 ISOCHORISMATASE
(Microbacterium
hydrocarbonoxyda
ns) 		4 / 6 ILE A  12
ARG A  77
THR A  88
LEU A  89
 None
 1.02A 5z86N-5ha8A:
undetectable
5z86W-5ha8A:
undetectable		 5z86N-5ha8A:
16.31
5z86W-5ha8A:
14.52