SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 8 GLY A 387
GLU A 219
PHE A 245
HIS A 248
 A  C   1 ( 3.7A)
None
A  C   2 ( 4.2A)
None
 0.87A 1ax9A-5habA:
undetectable		 1ax9A-5habA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 0.94A 1c6zB-5habA:
undetectable		 1c6zB-5habA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1c9sA-5habA:
undetectable
1c9sK-5habA:
undetectable		 1c9sA-5habA:
12.91
1c9sK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1c9sB-5habA:
undetectable
1c9sC-5habA:
undetectable		 1c9sB-5habA:
12.91
1c9sC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1c9sC-5habA:
undetectable
1c9sD-5habA:
undetectable		 1c9sC-5habA:
12.91
1c9sD-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1c9sD-5habA:
undetectable
1c9sE-5habA:
undetectable		 1c9sD-5habA:
12.91
1c9sE-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1c9sE-5habA:
undetectable
1c9sF-5habA:
undetectable		 1c9sE-5habA:
12.91
1c9sF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 1c9sF-5habA:
undetectable
1c9sG-5habA:
undetectable		 1c9sF-5habA:
12.91
1c9sG-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 1c9sG-5habA:
undetectable
1c9sH-5habA:
undetectable		 1c9sG-5habA:
12.91
1c9sH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 1c9sH-5habA:
undetectable
1c9sI-5habA:
undetectable		 1c9sH-5habA:
12.91
1c9sI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1c9sJ-5habA:
undetectable
1c9sK-5habA:
undetectable		 1c9sJ-5habA:
12.91
1c9sK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1c9sO-5habA:
0.0
1c9sP-5habA:
undetectable		 1c9sO-5habA:
12.91
1c9sP-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1gtfA-5habA:
undetectable
1gtfK-5habA:
undetectable		 1gtfA-5habA:
12.91
1gtfK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1gtfB-5habA:
undetectable
1gtfC-5habA:
undetectable		 1gtfB-5habA:
12.91
1gtfC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1gtfC-5habA:
undetectable
1gtfD-5habA:
undetectable		 1gtfC-5habA:
12.91
1gtfD-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1gtfE-5habA:
undetectable
1gtfF-5habA:
undetectable		 1gtfE-5habA:
12.91
1gtfF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1gtfG-5habA:
0.0
1gtfH-5habA:
undetectable		 1gtfG-5habA:
12.91
1gtfH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1gtfH-5habA:
undetectable
1gtfI-5habA:
undetectable		 1gtfH-5habA:
12.91
1gtfI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1gtfI-5habA:
undetectable
1gtfJ-5habA:
undetectable		 1gtfI-5habA:
12.91
1gtfJ-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1gtfP-5habA:
undetectable
1gtfQ-5habA:
undetectable		 1gtfP-5habA:
12.91
1gtfQ-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1gtfU-5habA:
undetectable
1gtfV-5habA:
undetectable		 1gtfU-5habA:
12.91
1gtfV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 1gtfL-5habA:
undetectable
1gtfV-5habA:
undetectable		 1gtfL-5habA:
12.91
1gtfV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.31A 1gtnG-5habA:
0.0
1gtnH-5habA:
undetectable		 1gtnG-5habA:
12.91
1gtnH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 1.11A 1sduB-5habA:
undetectable		 1sduB-5habA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1utdA-5habA:
undetectable
1utdB-5habA:
undetectable		 1utdA-5habA:
12.91
1utdB-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 1utdC-5habA:
undetectable
1utdD-5habA:
undetectable		 1utdC-5habA:
12.91
1utdD-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1utdD-5habA:
undetectable
1utdE-5habA:
undetectable		 1utdD-5habA:
12.91
1utdE-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 1utdG-5habA:
undetectable
1utdH-5habA:
0.0		 1utdG-5habA:
12.91
1utdH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1utdA-5habA:
undetectable
1utdK-5habA:
undetectable		 1utdA-5habA:
12.91
1utdK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1utdM-5habA:
undetectable
1utdN-5habA:
undetectable		 1utdM-5habA:
12.91
1utdN-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.29A 1utdN-5habA:
undetectable
1utdO-5habA:
undetectable		 1utdN-5habA:
12.91
1utdO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 1utdR-5habA:
undetectable
1utdS-5habA:
undetectable		 1utdR-5habA:
12.91
1utdS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 TYR A  12
ALA A  95
GLY A  34
ILE A  91
CYH A  80
 None
 1.08A 1x1aA-5habA:
3.1		 1x1aA-5habA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 1.01A 2avsB-5habA:
undetectable		 2avsB-5habA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 ARG A  36
ASN A 354
THR A 361
 None
None
A  C   2 ( 3.7A)
 0.84A 2q63A-5habA:
undetectable		 2q63A-5habA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 ASP A 188
THR A 105
PRO A 106
 None
 0.37A 2q64B-5habA:
undetectable		 2q64B-5habA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 8 HIS A  87
ASP A  32
ILE A  31
HIS A 410
 None
 1.01A 2xadA-5habA:
undetectable		 2xadA-5habA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 8 HIS A  87
ASP A  32
ILE A  31
HIS A 410
 None
 1.00A 2xadB-5habA:
undetectable		 2xadB-5habA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 8 HIS A  87
ASP A  32
ILE A  31
HIS A 410
 None
 1.02A 2xadC-5habA:
undetectable		 2xadC-5habA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 8 HIS A  87
ASP A  32
ILE A  31
HIS A 410
 None
 1.00A 2xadD-5habA:
undetectable		 2xadD-5habA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.42A 2zweA-5habA:
undetectable
2zweB-5habA:
undetectable		 2zweA-5habA:
20.76
2zweB-5habA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.39A 2zwfA-5habA:
undetectable
2zwfB-5habA:
undetectable		 2zwfA-5habA:
20.76
2zwfB-5habA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.40A 2zwgA-5habA:
undetectable
2zwgB-5habA:
undetectable		 2zwgA-5habA:
20.76
2zwgB-5habA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 PRO A 318
LEU A 269
ARG A 333
 None
 0.65A 3aqiB-5habA:
undetectable		 3aqiB-5habA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 ILE A   7
LEU A 437
ALA A 409
ILE A 407
ILE A 162
 None
 1.09A 3b2rA-5habA:
undetectable		 3b2rA-5habA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 ILE A   7
LEU A 437
ALA A 409
ILE A 407
ILE A 162
 None
 1.09A 3b2rB-5habA:
undetectable		 3b2rB-5habA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 1.02A 3cyxA-5habA:
undetectable		 3cyxA-5habA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 THR A  81
ALA A  77
THR A 164
VAL A  24
ILE A  22
 None
 1.01A 3czhA-5habA:
undetectable		 3czhA-5habA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 THR A  81
ALA A  77
THR A 164
VAL A  24
ILE A  22
 None
 1.06A 3czhB-5habA:
undetectable		 3czhB-5habA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 ARG A  17
THR A  81
THR A 208
 None
None
A  C   1 ( 4.4A)
 0.75A 3k2hB-5habA:
undetectable		 3k2hB-5habA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 0.94A 3nduD-5habA:
undetectable		 3nduD-5habA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B2000_1
(P38A)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 ILE A  31
ILE A 154
TYR A 107
ILE A 155
VAL A 160
 None
 1.15A 3ohtA-5habA:
undetectable
3ohtB-5habA:
undetectable		 3ohtA-5habA:
22.51
3ohtB-5habA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 1.06A 3oxxA-5habA:
undetectable		 3oxxA-5habA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 1.02A 3tkgC-5habA:
undetectable		 3tkgC-5habA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 ASP A 188
THR A 105
PRO A 106
 None
 0.41A 3tkgD-5habA:
undetectable		 3tkgD-5habA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 HIS A 152
HIS A  82
ILE A 154
 None
 0.81A 3u52A-5habA:
undetectable
3u52C-5habA:
undetectable		 3u52A-5habA:
22.03
3u52C-5habA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 ILE A 103
ILE A  31
ILE A  30
MET A  68
ILE A  22
 None
 1.09A 3zosA-5habA:
undetectable		 3zosA-5habA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 323
HIS A 152
PHE A 245
ASP A 174
ASP A  86
 A  C   2 ( 4.4A)
None
A  C   2 ( 4.2A)
A  C   2 ( 4.1A)
A  C   2 ( 3.5A)
 1.35A 4lxzB-5habA:
undetectable		 4lxzB-5habA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 ALA A 202
ILE A 143
GLY A 167
ILE A   6
VAL A  24
 None
 1.06A 4nkxA-5habA:
undetectable		 4nkxA-5habA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 7 HIS A  87
HIS A 410
HIS A 388
HIS A 152
 None
None
A  C   1 ( 4.3A)
None
 0.98A 4p6sB-5habA:
undetectable		 4p6sB-5habA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 LEU A 401
LEU A 203
GLU A 396
LEU A 397
ALA A 426
 None
 1.21A 4wg0H-5habA:
undetectable
4wg0I-5habA:
undetectable
4wg0J-5habA:
undetectable		 4wg0H-5habA:
3.56
4wg0I-5habA:
3.56
4wg0J-5habA:
3.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 6 LEU A 183
ASP A 178
ILE A 255
PRO A 217
 None
 1.08A 4xi3C-5habA:
undetectable		 4xi3C-5habA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  89
ASN A  18
ASP A  32
ALA A 104
ILE A 112
 None
 1.22A 4xj7A-5habA:
undetectable
4xj7B-5habA:
undetectable		 4xj7A-5habA:
22.88
4xj7B-5habA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 6 ASP A 174
ALA A 172
THR A 157
THR A 150
 A  C   2 ( 4.1A)
None
None
None
 1.32A 4z4fA-5habA:
undetectable		 4z4fA-5habA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 5 ASP A 174
ALA A 172
THR A 157
THR A 150
 A  C   2 ( 4.1A)
None
None
None
 1.33A 4z4gA-5habA:
undetectable		 4z4gA-5habA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 6 ASP A 174
ALA A 172
THR A 157
THR A 150
 A  C   2 ( 4.1A)
None
None
None
 1.29A 4z4iA-5habA:
3.3		 4z4iA-5habA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		4 / 7 GLY A  34
GLY A  16
GLU A  14
SER A 153
 None
None
None
A  C   1 ( 4.6A)
 0.96A 4z53A-5habA:
undetectable
4z53B-5habA:
undetectable		 4z53A-5habA:
22.50
4z53B-5habA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 HIS A 323
HIS A 152
PHE A 245
ASP A 174
ASP A  86
 A  C   2 ( 4.4A)
None
A  C   2 ( 4.2A)
A  C   2 ( 4.1A)
A  C   2 ( 3.5A)
 1.27A 5eenA-5habA:
undetectable		 5eenA-5habA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 HIS A 323
HIS A 152
PHE A 245
ASP A 174
ASP A  86
 A  C   2 ( 4.4A)
None
A  C   2 ( 4.2A)
A  C   2 ( 4.1A)
A  C   2 ( 3.5A)
 1.28A 5eenB-5habA:
2.1		 5eenB-5habA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eeuB-5habA:
undetectable
5eeuC-5habA:
undetectable		 5eeuB-5habA:
12.91
5eeuC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeuE-5habA:
0.0
5eeuF-5habA:
undetectable		 5eeuE-5habA:
12.91
5eeuF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeuG-5habA:
undetectable
5eeuH-5habA:
undetectable		 5eeuG-5habA:
12.91
5eeuH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eeuH-5habA:
undetectable
5eeuI-5habA:
undetectable		 5eeuH-5habA:
12.91
5eeuI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeuJ-5habA:
undetectable
5eeuK-5habA:
undetectable		 5eeuJ-5habA:
12.91
5eeuK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5eeuA-5habA:
undetectable
5eeuK-5habA:
undetectable		 5eeuA-5habA:
12.91
5eeuK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeuN-5habA:
undetectable
5eeuO-5habA:
undetectable		 5eeuN-5habA:
12.91
5eeuO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eeuR-5habA:
undetectable
5eeuS-5habA:
undetectable		 5eeuR-5habA:
12.91
5eeuS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeuS-5habA:
undetectable
5eeuT-5habA:
undetectable		 5eeuS-5habA:
12.91
5eeuT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeuT-5habA:
undetectable
5eeuU-5habA:
undetectable		 5eeuT-5habA:
12.91
5eeuU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeuU-5habA:
undetectable
5eeuV-5habA:
undetectable		 5eeuU-5habA:
12.91
5eeuV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eevB-5habA:
undetectable
5eevC-5habA:
undetectable		 5eevB-5habA:
12.91
5eevC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eevE-5habA:
0.0
5eevF-5habA:
undetectable		 5eevE-5habA:
12.91
5eevF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eevG-5habA:
undetectable
5eevH-5habA:
undetectable		 5eevG-5habA:
12.91
5eevH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eevH-5habA:
undetectable
5eevI-5habA:
undetectable		 5eevH-5habA:
12.91
5eevI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eevJ-5habA:
undetectable
5eevK-5habA:
undetectable		 5eevJ-5habA:
12.91
5eevK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5eevA-5habA:
undetectable
5eevK-5habA:
undetectable		 5eevA-5habA:
12.91
5eevK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eevN-5habA:
undetectable
5eevO-5habA:
undetectable		 5eevN-5habA:
12.91
5eevO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eevR-5habA:
undetectable
5eevS-5habA:
undetectable		 5eevR-5habA:
12.91
5eevS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eevS-5habA:
undetectable
5eevT-5habA:
undetectable		 5eevS-5habA:
12.91
5eevT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eevT-5habA:
undetectable
5eevU-5habA:
undetectable		 5eevT-5habA:
12.91
5eevU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eevU-5habA:
undetectable
5eevV-5habA:
undetectable		 5eevU-5habA:
12.91
5eevV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eewB-5habA:
undetectable
5eewC-5habA:
undetectable		 5eewB-5habA:
12.91
5eewC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eewE-5habA:
0.0
5eewF-5habA:
undetectable		 5eewE-5habA:
12.91
5eewF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eewG-5habA:
undetectable
5eewH-5habA:
undetectable		 5eewG-5habA:
12.91
5eewH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eewH-5habA:
undetectable
5eewI-5habA:
undetectable		 5eewH-5habA:
12.91
5eewI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eewJ-5habA:
undetectable
5eewK-5habA:
undetectable		 5eewJ-5habA:
12.91
5eewK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5eewA-5habA:
undetectable
5eewK-5habA:
undetectable		 5eewA-5habA:
12.91
5eewK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eewN-5habA:
undetectable
5eewO-5habA:
undetectable		 5eewN-5habA:
12.91
5eewO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eewR-5habA:
undetectable
5eewS-5habA:
undetectable		 5eewR-5habA:
12.91
5eewS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eewS-5habA:
undetectable
5eewT-5habA:
undetectable		 5eewS-5habA:
12.91
5eewT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eewT-5habA:
undetectable
5eewU-5habA:
undetectable		 5eewT-5habA:
12.91
5eewU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eewU-5habA:
undetectable
5eewV-5habA:
undetectable		 5eewU-5habA:
12.91
5eewV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eexB-5habA:
undetectable
5eexC-5habA:
undetectable		 5eexB-5habA:
12.91
5eexC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eexE-5habA:
0.0
5eexF-5habA:
undetectable		 5eexE-5habA:
12.91
5eexF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eexG-5habA:
undetectable
5eexH-5habA:
undetectable		 5eexG-5habA:
12.91
5eexH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eexH-5habA:
undetectable
5eexI-5habA:
undetectable		 5eexH-5habA:
12.91
5eexI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eexI-5habA:
undetectable
5eexJ-5habA:
undetectable		 5eexI-5habA:
12.91
5eexJ-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eexJ-5habA:
undetectable
5eexK-5habA:
undetectable		 5eexJ-5habA:
12.91
5eexK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5eexA-5habA:
undetectable
5eexK-5habA:
undetectable		 5eexA-5habA:
12.91
5eexK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eexN-5habA:
undetectable
5eexO-5habA:
undetectable		 5eexN-5habA:
12.91
5eexO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eexQ-5habA:
undetectable
5eexR-5habA:
undetectable		 5eexQ-5habA:
12.91
5eexR-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eexR-5habA:
undetectable
5eexS-5habA:
undetectable		 5eexR-5habA:
12.91
5eexS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eexS-5habA:
undetectable
5eexT-5habA:
undetectable		 5eexS-5habA:
12.91
5eexT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eexT-5habA:
undetectable
5eexU-5habA:
undetectable		 5eexT-5habA:
12.91
5eexU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eexU-5habA:
undetectable
5eexV-5habA:
undetectable		 5eexU-5habA:
12.91
5eexV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eeyB-5habA:
0.0
5eeyC-5habA:
undetectable		 5eeyB-5habA:
12.91
5eeyC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeyE-5habA:
0.0
5eeyF-5habA:
undetectable		 5eeyE-5habA:
12.91
5eeyF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeyG-5habA:
undetectable
5eeyH-5habA:
undetectable		 5eeyG-5habA:
12.91
5eeyH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eeyH-5habA:
undetectable
5eeyI-5habA:
undetectable		 5eeyH-5habA:
12.91
5eeyI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyI-5habA:
undetectable
5eeyJ-5habA:
undetectable		 5eeyI-5habA:
12.91
5eeyJ-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyJ-5habA:
undetectable
5eeyK-5habA:
0.0		 5eeyJ-5habA:
12.91
5eeyK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyA-5habA:
undetectable
5eeyK-5habA:
0.0		 5eeyA-5habA:
12.91
5eeyK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyN-5habA:
undetectable
5eeyO-5habA:
undetectable		 5eeyN-5habA:
12.91
5eeyO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyQ-5habA:
undetectable
5eeyR-5habA:
undetectable		 5eeyQ-5habA:
12.91
5eeyR-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eeyR-5habA:
undetectable
5eeyS-5habA:
undetectable		 5eeyR-5habA:
12.91
5eeyS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeyS-5habA:
undetectable
5eeyT-5habA:
undetectable		 5eeyS-5habA:
12.91
5eeyT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eeyT-5habA:
undetectable
5eeyU-5habA:
undetectable		 5eeyT-5habA:
12.91
5eeyU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eeyU-5habA:
undetectable
5eeyV-5habA:
undetectable		 5eeyU-5habA:
12.91
5eeyV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eezB-5habA:
undetectable
5eezC-5habA:
undetectable		 5eezB-5habA:
12.91
5eezC-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eezE-5habA:
0.0
5eezF-5habA:
undetectable		 5eezE-5habA:
12.91
5eezF-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eezG-5habA:
undetectable
5eezH-5habA:
undetectable		 5eezG-5habA:
12.91
5eezH-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5eezH-5habA:
undetectable
5eezI-5habA:
undetectable		 5eezH-5habA:
12.91
5eezI-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eezI-5habA:
undetectable
5eezJ-5habA:
undetectable		 5eezI-5habA:
12.91
5eezJ-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eezJ-5habA:
undetectable
5eezK-5habA:
0.0		 5eezJ-5habA:
12.91
5eezK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5eezA-5habA:
undetectable
5eezK-5habA:
0.0		 5eezA-5habA:
12.91
5eezK-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eezN-5habA:
undetectable
5eezO-5habA:
undetectable		 5eezN-5habA:
12.91
5eezO-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eezQ-5habA:
undetectable
5eezR-5habA:
undetectable		 5eezQ-5habA:
12.91
5eezR-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5eezR-5habA:
undetectable
5eezS-5habA:
undetectable		 5eezR-5habA:
12.91
5eezS-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eezS-5habA:
undetectable
5eezT-5habA:
undetectable		 5eezS-5habA:
12.91
5eezT-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5eezT-5habA:
undetectable
5eezU-5habA:
undetectable		 5eezT-5habA:
12.91
5eezU-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5eezU-5habA:
undetectable
5eezV-5habA:
undetectable		 5eezU-5habA:
12.91
5eezV-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef0B-5habA:
0.0
5ef0C-5habA:
undetectable		 5ef0B-5habA:
12.91
5ef0C-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef0E-5habA:
0.0
5ef0F-5habA:
undetectable		 5ef0E-5habA:
12.91
5ef0F-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef0G-5habA:
undetectable
5ef0H-5habA:
undetectable		 5ef0G-5habA:
12.91
5ef0H-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5ef0H-5habA:
undetectable
5ef0I-5habA:
undetectable		 5ef0H-5habA:
12.91
5ef0I-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0I-5habA:
undetectable
5ef0J-5habA:
undetectable		 5ef0I-5habA:
12.91
5ef0J-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0J-5habA:
undetectable
5ef0K-5habA:
0.0		 5ef0J-5habA:
12.91
5ef0K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0A-5habA:
undetectable
5ef0K-5habA:
0.0		 5ef0A-5habA:
12.91
5ef0K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0N-5habA:
undetectable
5ef0O-5habA:
undetectable		 5ef0N-5habA:
12.91
5ef0O-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0Q-5habA:
undetectable
5ef0R-5habA:
undetectable		 5ef0Q-5habA:
12.91
5ef0R-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef0R-5habA:
undetectable
5ef0S-5habA:
undetectable		 5ef0R-5habA:
12.91
5ef0S-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef0S-5habA:
undetectable
5ef0T-5habA:
undetectable		 5ef0S-5habA:
12.91
5ef0T-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef0T-5habA:
undetectable
5ef0U-5habA:
undetectable		 5ef0T-5habA:
12.91
5ef0U-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef0U-5habA:
undetectable
5ef0V-5habA:
undetectable		 5ef0U-5habA:
12.91
5ef0V-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef1B-5habA:
0.0
5ef1C-5habA:
undetectable		 5ef1B-5habA:
12.91
5ef1C-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef1E-5habA:
0.0
5ef1F-5habA:
undetectable		 5ef1E-5habA:
12.91
5ef1F-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef1G-5habA:
undetectable
5ef1H-5habA:
undetectable		 5ef1G-5habA:
12.91
5ef1H-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5ef1H-5habA:
undetectable
5ef1I-5habA:
undetectable		 5ef1H-5habA:
12.91
5ef1I-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef1I-5habA:
undetectable
5ef1J-5habA:
undetectable		 5ef1I-5habA:
12.91
5ef1J-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef1J-5habA:
undetectable
5ef1K-5habA:
undetectable		 5ef1J-5habA:
12.91
5ef1K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5ef1A-5habA:
undetectable
5ef1K-5habA:
undetectable		 5ef1A-5habA:
12.91
5ef1K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef1N-5habA:
undetectable
5ef1O-5habA:
undetectable		 5ef1N-5habA:
12.91
5ef1O-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef1Q-5habA:
undetectable
5ef1R-5habA:
undetectable		 5ef1Q-5habA:
12.91
5ef1R-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef1R-5habA:
undetectable
5ef1S-5habA:
undetectable		 5ef1R-5habA:
12.91
5ef1S-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef1S-5habA:
undetectable
5ef1T-5habA:
undetectable		 5ef1S-5habA:
12.91
5ef1T-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef1T-5habA:
undetectable
5ef1U-5habA:
undetectable		 5ef1T-5habA:
12.91
5ef1U-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef1U-5habA:
undetectable
5ef1V-5habA:
undetectable		 5ef1U-5habA:
12.91
5ef1V-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef2B-5habA:
undetectable
5ef2C-5habA:
undetectable		 5ef2B-5habA:
12.91
5ef2C-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef2E-5habA:
0.0
5ef2F-5habA:
undetectable		 5ef2E-5habA:
12.91
5ef2F-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef2G-5habA:
undetectable
5ef2H-5habA:
undetectable		 5ef2G-5habA:
12.91
5ef2H-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5ef2H-5habA:
undetectable
5ef2I-5habA:
undetectable		 5ef2H-5habA:
12.91
5ef2I-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef2I-5habA:
undetectable
5ef2J-5habA:
undetectable		 5ef2I-5habA:
12.91
5ef2J-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef2J-5habA:
undetectable
5ef2K-5habA:
undetectable		 5ef2J-5habA:
12.91
5ef2K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5ef2A-5habA:
undetectable
5ef2K-5habA:
undetectable		 5ef2A-5habA:
12.91
5ef2K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef2N-5habA:
undetectable
5ef2O-5habA:
undetectable		 5ef2N-5habA:
12.91
5ef2O-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef2Q-5habA:
undetectable
5ef2R-5habA:
undetectable		 5ef2Q-5habA:
12.91
5ef2R-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef2R-5habA:
undetectable
5ef2S-5habA:
undetectable		 5ef2R-5habA:
12.91
5ef2S-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef2S-5habA:
undetectable
5ef2T-5habA:
undetectable		 5ef2S-5habA:
12.91
5ef2T-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef2T-5habA:
undetectable
5ef2U-5habA:
undetectable		 5ef2T-5habA:
12.91
5ef2U-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef2U-5habA:
undetectable
5ef2V-5habA:
undetectable		 5ef2U-5habA:
12.91
5ef2V-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef3B-5habA:
undetectable
5ef3C-5habA:
undetectable		 5ef3B-5habA:
12.91
5ef3C-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef3E-5habA:
0.0
5ef3F-5habA:
undetectable		 5ef3E-5habA:
12.91
5ef3F-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef3G-5habA:
undetectable
5ef3H-5habA:
undetectable		 5ef3G-5habA:
12.91
5ef3H-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.27A 5ef3H-5habA:
undetectable
5ef3I-5habA:
undetectable		 5ef3H-5habA:
12.91
5ef3I-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef3I-5habA:
undetectable
5ef3J-5habA:
undetectable		 5ef3I-5habA:
12.91
5ef3J-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef3J-5habA:
undetectable
5ef3K-5habA:
undetectable		 5ef3J-5habA:
12.91
5ef3K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.24A 5ef3A-5habA:
undetectable
5ef3K-5habA:
undetectable		 5ef3A-5habA:
12.91
5ef3K-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef3N-5habA:
undetectable
5ef3O-5habA:
undetectable		 5ef3N-5habA:
12.91
5ef3O-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef3Q-5habA:
undetectable
5ef3R-5habA:
undetectable		 5ef3Q-5habA:
12.91
5ef3R-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.28A 5ef3R-5habA:
undetectable
5ef3S-5habA:
undetectable		 5ef3R-5habA:
12.91
5ef3S-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef3S-5habA:
undetectable
5ef3T-5habA:
undetectable		 5ef3S-5habA:
12.91
5ef3T-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.25A 5ef3T-5habA:
undetectable
5ef3U-5habA:
undetectable		 5ef3T-5habA:
12.91
5ef3U-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 GLY A  83
HIS A  87
THR A 105
THR A 108
ILE A 112
 None
 1.26A 5ef3U-5habA:
undetectable
5ef3V-5habA:
undetectable		 5ef3U-5habA:
12.91
5ef3V-5habA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 HIS A 323
HIS A 152
PHE A 245
ASP A 174
ASP A  86
 A  C   2 ( 4.4A)
None
A  C   2 ( 4.2A)
A  C   2 ( 4.1A)
A  C   2 ( 3.5A)
 1.24A 5ef8A-5habA:
undetectable		 5ef8A-5habA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 ILE A 154
HIS A  82
THR A 208
GLU A 206
ALA A 104
 None
None
A  C   1 ( 4.4A)
None
None
 1.19A 5iwuA-5habA:
undetectable		 5iwuA-5habA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 9 LEU A 137
VAL A 160
ILE A  31
ILE A 102
ILE A 145
 None
 1.12A 5kqxB-5habA:
undetectable		 5kqxB-5habA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 10 HIS A  82
HIS A  87
HIS A 152
ASP A 174
HIS A 388
 None
None
None
A  C   2 ( 4.1A)
A  C   1 ( 4.3A)
 0.85A 5nzwA-5habA:
9.0		 5nzwA-5habA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 THR A 208
GLU A 206
HIS A 152
 A  C   1 ( 4.4A)
None
None
 0.74A 5xioA-5habA:
undetectable		 5xioA-5habA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 THR A 208
GLU A 206
HIS A 152
 A  C   1 ( 4.4A)
None
None
 0.76A 5xiqB-5habA:
undetectable		 5xiqB-5habA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		3 / 3 THR A 208
GLU A 206
HIS A 152
 A  C   1 ( 4.4A)
None
None
 0.76A 5xiqD-5habA:
undetectable		 5xiqD-5habA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.39A 5z0fA-5habA:
undetectable
5z0fB-5habA:
undetectable		 5z0fA-5habA:
11.27
5z0fB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.39A 5z0hA-5habA:
undetectable
5z0hB-5habA:
undetectable		 5z0hA-5habA:
11.27
5z0hB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.39A 5z0iA-5habA:
undetectable
5z0iB-5habA:
undetectable		 5z0iA-5habA:
11.27
5z0iB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.40A 5z0jA-5habA:
undetectable
5z0jB-5habA:
undetectable		 5z0jA-5habA:
11.27
5z0jB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.40A 5z0lA-5habA:
undetectable
5z0lB-5habA:
undetectable		 5z0lA-5habA:
11.27
5z0lB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 11 HIS A 152
HIS A 388
HIS A 410
ASN A  18
HIS A  87
 None
A  C   1 ( 4.3A)
None
None
None
 1.39A 5z0mA-5habA:
undetectable
5z0mB-5habA:
undetectable		 5z0mA-5habA:
9.96
5z0mB-5habA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 5hab RIBONUCLEASE J
(Methanolobus
psychrophilus) 		5 / 12 GLY A 376
ALA A 377
ASP A 347
ILE A 241
ILE A 379
 None
 0.98A 6dh6A-5habA:
undetectable		 6dh6A-5habA:
11.82