SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5haf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.26A 1p6kB-5hafA:
undetectable		 1p6kB-5hafA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.26A 1rs6A-5hafA:
undetectable		 1rs6A-5hafA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.23A 1rs6B-5hafA:
undetectable		 1rs6B-5hafA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.16A 1rs7B-5hafA:
undetectable		 1rs7B-5hafA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 CYH A  48
ALA A  51
ALA A 118
VAL A  89
ALA A  86
 None
 1.12A 1sa1A-5hafA:
undetectable
1sa1B-5hafA:
undetectable		 1sa1A-5hafA:
20.48
1sa1B-5hafA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.27A 1zzqA-5hafA:
undetectable		 1zzqA-5hafA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.22A 1zzqB-5hafA:
undetectable		 1zzqB-5hafA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.27A 1zzuB-5hafA:
undetectable		 1zzuB-5hafA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		3 / 3 ASN A 219
LEU A 225
HIS A 223
 None
 0.79A 2q6fB-5hafA:
undetectable		 2q6fB-5hafA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 GLN A 200
LEU A 197
LEU A 225
CYH A 289
THR A 292
 None
 1.42A 3cldA-5hafA:
undetectable		 3cldA-5hafA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 THR A 220
GLY A 186
HIS A 223
GLN A 278
THR A 243
 None
 1.09A 3eeyC-5hafA:
undetectable		 3eeyC-5hafA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 THR A 220
GLY A 186
HIS A 223
GLN A 278
THR A 243
 None
 1.09A 3eeyE-5hafA:
undetectable		 3eeyE-5hafA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 THR A 220
GLY A 186
HIS A 223
GLN A 278
THR A 243
 None
 1.12A 3eeyF-5hafA:
undetectable		 3eeyF-5hafA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 LEU A 172
GLY A 171
TYR A 290
ILE A 293
LEU A 217
 None
 1.04A 3gwvA-5hafA:
undetectable		 3gwvA-5hafA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.25A 3n62A-5hafA:
undetectable		 3n62A-5hafA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.30A 3n62B-5hafA:
undetectable		 3n62B-5hafA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.33A 3n66B-5hafA:
undetectable		 3n66B-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		3 / 3 PRO A 304
ASN A 213
HIS A 212
 None
 0.79A 4ma3H-5hafA:
undetectable
4ma3L-5hafA:
undetectable		 4ma3H-5hafA:
17.75
4ma3L-5hafA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 7 GLU A 310
LEU A 308
ASN A 271
LEU A 239
LEU A 228
 None
 1.36A 4wg0B-5hafA:
undetectable
4wg0C-5hafA:
undetectable		 4wg0B-5hafA:
3.62
4wg0C-5hafA:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 5 ASP A  67
ASP A  80
PHE A  33
GLY A  75
 None
 1.12A 4xp6A-5hafA:
undetectable		 4xp6A-5hafA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.33A 5vunA-5hafA:
undetectable		 5vunA-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.28A 5vunB-5hafA:
undetectable		 5vunB-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.27A 5vuoB-5hafA:
undetectable		 5vuoB-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		4 / 8 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.30A 6auuB-5hafA:
undetectable		 6auuB-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5haf DEUBIQUITINASE SSEL
(Salmonella
enterica) 		5 / 12 VAL A 270
ILE A 196
ILE A 240
PHE A 229
PHE A 216
 None
 1.39A 6j20A-5hafA:
undetectable		 6j20A-5hafA:
19.60