SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5has'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.75A 1a7yA-5hasA:
undetectable		 1a7yA-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.73A 1a7yB-5hasA:
undetectable		 1a7yB-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.67A 1fjaC-5hasA:
undetectable		 1fjaC-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.67A 1fjaD-5hasA:
undetectable		 1fjaD-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.71A 1i3wE-5hasA:
undetectable		 1i3wE-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.75A 1i3wE-5hasA:
undetectable		 1i3wE-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.75A 1i3wF-5hasA:
undetectable		 1i3wF-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.70A 1i3wG-5hasA:
undetectable		 1i3wG-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.78A 1i3wG-5hasA:
undetectable		 1i3wG-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.77A 1i3wH-5hasA:
undetectable		 1i3wH-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 5has SEC7
(Thielavia
terrestris) 		4 / 7 PHE A 376
ALA A 309
PHE A 177
PHE A 313
 None
 1.22A 1lqtA-5hasA:
undetectable		 1lqtA-5hasA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 5has SEC7
(Thielavia
terrestris) 		4 / 7 PHE A 376
ALA A 309
PHE A 177
PHE A 313
 None
 1.22A 1lquA-5hasA:
undetectable		 1lquA-5hasA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.83A 1mnvD-5hasA:
undetectable		 1mnvD-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.75A 1mnvD-5hasA:
undetectable		 1mnvD-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.77A 1ovfB-5hasA:
undetectable		 1ovfB-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.78A 1qfiA-5hasA:
undetectable		 1qfiA-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.72A 1qfiB-5hasA:
undetectable		 1qfiB-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.82A 1unjF-5hasA:
undetectable		 1unjF-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.79A 1unjF-5hasA:
undetectable		 1unjF-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.77A 1unjL-5hasA:
undetectable		 1unjL-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.77A 1unjL-5hasA:
undetectable		 1unjL-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.78A 1unjR-5hasA:
undetectable		 1unjR-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.79A 1unjW-5hasA:
undetectable		 1unjW-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.78A 1unjX-5hasA:
undetectable		 1unjX-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.78A 1unjX-5hasA:
undetectable		 1unjX-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.77A 1unmE-5hasA:
undetectable		 1unmE-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.75A 1unmE-5hasA:
undetectable		 1unmE-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.75A 1unmF-5hasA:
undetectable		 1unmF-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.72A 1unmF-5hasA:
undetectable		 1unmF-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAO_A_ACTA601_0
(VANILLYL-ALCOHOL
OXIDASE)		 5has SEC7
(Thielavia
terrestris) 		4 / 5 TYR A 310
PHE A 256
TYR A 383
ARG A 314
 None
 1.25A 1vaoA-5hasA:
0.4		 1vaoA-5hasA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAO_B_ACTB601_0
(VANILLYL-ALCOHOL
OXIDASE)		 5has SEC7
(Thielavia
terrestris) 		4 / 5 TYR A 310
PHE A 256
TYR A 383
ARG A 314
 None
 1.25A 1vaoB-5hasA:
undetectable		 1vaoB-5hasA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  64
PRO A  62
THR A  66
 None
 0.55A 209dC-5hasA:
undetectable		 209dC-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 THR A  66
THR A  64
PRO A  62
 None
 0.65A 209dC-5hasA:
undetectable		 209dC-5hasA:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5has SEC7
(Thielavia
terrestris) 		3 / 3 LYS A  42
TYR A  79
PRO A  43
 None
 1.39A 2j9cC-5hasA:
undetectable		 2j9cC-5hasA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5has SEC7
(Thielavia
terrestris) 		4 / 5 PHE A 376
PHE A 358
HIS A 354
VAL A 180
 None
 1.25A 2lh6A-5hasA:
undetectable		 2lh6A-5hasA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5has SEC7
(Thielavia
terrestris) 		5 / 12 LEU A 131
ASN A 132
LEU A 127
VAL A 146
LEU A 142
 None
 1.06A 2q7kA-5hasA:
undetectable		 2q7kA-5hasA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5has SEC7
(Thielavia
terrestris) 		5 / 12 LEU A 169
PHE A 177
ILE A 355
ASN A 352
VAL A 357
 None
 1.06A 2zzmA-5hasA:
undetectable		 2zzmA-5hasA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5has SEC7
(Thielavia
terrestris) 		5 / 12 LEU A 169
PHE A 177
ILE A 355
ASN A 352
VAL A 357
 None
 1.12A 2zznA-5hasA:
undetectable		 2zznA-5hasA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5has SEC7
(Thielavia
terrestris) 		4 / 8 LEU A  11
SER A  10
THR A  66
ALA A  55
 None
 0.82A 3ax9B-5hasA:
undetectable		 3ax9B-5hasA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 5has SEC7
(Thielavia
terrestris) 		5 / 12 ASP A 308
GLY A 139
SER A 269
VAL A 176
ALA A 304
 None
 1.19A 3d91B-5hasA:
undetectable		 3d91B-5hasA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 5has SEC7
(Thielavia
terrestris) 		4 / 8 TYR A 383
TYR A 382
SER A 320
ILE A 347
 None
 0.90A 3jz0B-5hasA:
1.5		 3jz0B-5hasA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5has SEC7
(Thielavia
terrestris) 		4 / 8 SER A 315
ASN A 318
MET A 261
GLY A 262
 None
 0.76A 4fo4A-5hasA:
undetectable		 4fo4A-5hasA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5has SEC7
(Thielavia
terrestris) 		4 / 4 ILE A 152
GLY A 111
ILE A 122
LEU A 155
 None
 0.87A 5dzkl-5hasA:
undetectable
5dzkz-5hasA:
undetectable		 5dzkl-5hasA:
17.36
5dzkz-5hasA:
1.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 5has SEC7
(Thielavia
terrestris) 		4 / 5 ALA A  55
ALA A  67
ILE A  14
LEU A  11
 None
 0.73A 5jncD-5hasA:
undetectable		 5jncD-5hasA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5has SEC7
(Thielavia
terrestris) 		4 / 7 LEU A 346
PHE A 316
SER A 320
ILE A 380
 None
 0.96A 5n5dA-5hasA:
undetectable		 5n5dA-5hasA:
17.86