SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 PHE A 150
LEU A 234
VAL A 220
GLY A 219
VAL A 192
 None
 1.24A 1akdA-5haxA:
undetectable		 1akdA-5haxA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 ILE A 646
GLY A 733
ALA A 756
GLY A 650
SER A 670
 None
 1.12A 1kiaA-5haxA:
undetectable		 1kiaA-5haxA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 ILE A 646
GLY A 733
ALA A 756
GLY A 650
SER A 670
 None
 1.04A 1nbiA-5haxA:
undetectable		 1nbiA-5haxA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 ILE A 646
GLY A 733
ALA A 756
GLY A 650
SER A 670
 None
 1.03A 1nbiB-5haxA:
undetectable		 1nbiB-5haxA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 LEU A 763
LEU A 760
LEU A 757
ALA A 756
LEU A 669
 None
 0.92A 1s9pC-5haxA:
undetectable		 1s9pC-5haxA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 LEU A 763
LEU A 760
LEU A 757
GLU A 753
LEU A 669
 None
 0.79A 1s9pC-5haxA:
undetectable		 1s9pC-5haxA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 LEU A 261
GLY A 253
TYR A 274
ILE A 272
VAL A 208
 None
 1.14A 1tmxB-5haxA:
undetectable		 1tmxB-5haxA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 10 THR A 531
VAL A 561
VAL A 567
VAL A 125
VAL A 124
 None
 1.11A 2qboA-5haxA:
undetectable		 2qboA-5haxA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 PHE A 723
ALA A 756
ALA A 618
ALA A 614
THR A 610
 None
 1.13A 2x2nB-5haxA:
undetectable		 2x2nB-5haxA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 8 LEU A 207
ALA A 222
LEU A 232
ILE A 259
 None
 0.85A 3cldB-5haxA:
undetectable		 3cldB-5haxA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 LEU A 562
GLY A 178
ALA A 156
LEU A 232
ILE A 177
 None
 1.13A 3ku1G-5haxA:
undetectable		 3ku1G-5haxA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		6 / 12 LEU A 562
VAL A 209
GLY A 178
ALA A 156
LEU A 232
ILE A 177
 None
 1.45A 3ku1H-5haxA:
undetectable		 3ku1H-5haxA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 GLY A 474
MET A 395
LEU A 397
ILE A 528
PHE A 471
 None
 1.29A 3mnoA-5haxA:
undetectable		 3mnoA-5haxA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 PHE A 434
GLN A 454
PHE A 362
 None
 0.81A 3rv5A-5haxA:
1.3		 3rv5A-5haxA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 8 ASP A 495
GLY A 497
GLU A 111
ARG A 572
 None
 1.02A 3s3nA-5haxA:
undetectable		 3s3nA-5haxA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 HIS A 758
SER A 766
GLU A 765
 None
 0.92A 3s8pA-5haxA:
undetectable		 3s8pA-5haxA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 SER A 703
ILE A 771
VAL A 774
LEU A 775
PHE A 778
 None
 1.18A 3w68A-5haxA:
undetectable		 3w68A-5haxA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 4 TRP A 688
LEU A 763
LEU A 680
THR A 681
 None
 1.13A 4bboD-5haxA:
undetectable		 4bboD-5haxA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 GLY A 545
ASN A 546
GLN A 551
PRO A 494
ILE A 499
 None
 1.42A 4j4vD-5haxA:
0.7
4j4vE-5haxA:
undetectable		 4j4vD-5haxA:
15.85
4j4vE-5haxA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 LEU A 406
MET A 427
ASP A 374
 None
 0.77A 4j7xB-5haxA:
undetectable		 4j7xB-5haxA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 SER A 382
ASP A 478
ASP A 487
 None
 0.89A 4mwzA-5haxA:
undetectable		 4mwzA-5haxA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 7 PHE A 601
ILE A 578
ASN A 585
ARG A 573
 None
 1.20A 4o7gA-5haxA:
2.7
4o7gB-5haxA:
2.2		 4o7gA-5haxA:
15.50
4o7gB-5haxA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.31A 4qvpV-5haxA:
undetectable
4qvpb-5haxA:
undetectable		 4qvpV-5haxA:
15.06
4qvpb-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.32A 4qvqH-5haxA:
undetectable
4qvqN-5haxA:
undetectable		 4qvqH-5haxA:
15.06
4qvqN-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.32A 4qvwH-5haxA:
undetectable
4qvwN-5haxA:
undetectable		 4qvwH-5haxA:
15.06
4qvwN-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.31A 4qwuV-5haxA:
undetectable
4qwub-5haxA:
undetectable		 4qwuV-5haxA:
15.06
4qwub-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.31A 4qwuH-5haxA:
undetectable
4qwuN-5haxA:
undetectable		 4qwuH-5haxA:
15.06
4qwuN-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 LEU A 724
LEU A 720
LEU A 676
ALA A 614
LEU A 615
 None
 1.15A 4wg0B-5haxA:
undetectable
4wg0C-5haxA:
undetectable
4wg0D-5haxA:
undetectable		 4wg0B-5haxA:
1.82
4wg0C-5haxA:
1.82
4wg0D-5haxA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 LEU A 724
LEU A 720
LEU A 676
ALA A 614
LEU A 615
 None
 1.14A 4wg0D-5haxA:
undetectable
4wg0E-5haxA:
undetectable
4wg0F-5haxA:
undetectable		 4wg0D-5haxA:
1.82
4wg0E-5haxA:
1.82
4wg0F-5haxA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 ALA A 614
LEU A 615
LEU A 676
LEU A 724
LEU A 720
 None
 1.13A 4wg0G-5haxA:
undetectable
4wg0H-5haxA:
undetectable
4wg0I-5haxA:
undetectable		 4wg0G-5haxA:
1.82
4wg0H-5haxA:
1.82
4wg0I-5haxA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 LEU A 724
LEU A 720
LEU A 676
ALA A 614
LEU A 615
 None
 1.12A 4wg0J-5haxA:
undetectable
4wg0K-5haxA:
undetectable
4wg0L-5haxA:
undetectable		 4wg0J-5haxA:
1.82
4wg0K-5haxA:
1.82
4wg0L-5haxA:
1.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.32A 5cz7H-5haxA:
undetectable
5cz7N-5haxA:
undetectable		 5cz7H-5haxA:
15.06
5cz7N-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 5 PRO A 556
LEU A 678
TYR A 605
PHE A 601
 None
 1.32A 5igjA-5haxA:
3.2		 5igjA-5haxA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 LEU A 462
TYR A 110
SER A 492
 None
 0.78A 5iktA-5haxA:
undetectable		 5iktA-5haxA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.31A 5l66V-5haxA:
undetectable
5l66b-5haxA:
undetectable		 5l66V-5haxA:
15.06
5l66b-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 11 HIS A 568
THR A 525
GLY A 529
ALA A 560
THR A 531
 None
 1.31A 5l66H-5haxA:
undetectable
5l66N-5haxA:
undetectable		 5l66H-5haxA:
15.06
5l66N-5haxA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 6 GLU A 718
ARG A 721
LEU A 720
ARG A 719
 None
 1.14A 5l6eA-5haxA:
undetectable
5l6eB-5haxA:
undetectable		 5l6eA-5haxA:
15.51
5l6eB-5haxA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 6 PRO A 385
PRO A 534
PHE A 535
LEU A 530
 None
 0.88A 5tl8A-5haxA:
undetectable		 5tl8A-5haxA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 GLY A 622
THR A 531
PRO A 556
 None
 0.57A 5v5zA-5haxA:
undetectable		 5v5zA-5haxA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		4 / 7 GLY A 474
GLN A 604
TYR A 605
TYR A 110
 None
 1.27A 5vlmG-5haxA:
2.9		 5vlmG-5haxA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 VAL A 608
GLU A 609
LEU A 724
LEU A 734
LEU A 720
 None
 1.01A 6ew0B-5haxA:
undetectable		 6ew0B-5haxA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 VAL A 608
GLU A 609
LEU A 724
LEU A 734
LEU A 720
 None
 1.01A 6ew0D-5haxA:
undetectable		 6ew0D-5haxA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 VAL A 608
GLU A 609
LEU A 724
LEU A 734
LEU A 720
 None
 1.01A 6ew0H-5haxA:
undetectable		 6ew0H-5haxA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		5 / 12 VAL A 608
GLU A 609
LEU A 724
LEU A 734
LEU A 720
 None
 1.01A 6ew0I-5haxA:
undetectable		 6ew0I-5haxA:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5hax NUCLEOPORIN NUP170
(Chaetomium
thermophilum) 		3 / 3 VAL A 576
ALA A 616
GLN A 551
 None
 0.56A 6gb9A-5haxA:
undetectable		 6gb9A-5haxA:
22.16