SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 6 HIS A1499
LEU A1000
LEU A1003
PRO A1004
 None
 1.26A 1hz4A-5hccA:
0.0		 1hz4A-5hccA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 MET A1057
SER A1103
ALA A1082
SER A1099
 EDO  A2003 (-4.2A)
None
None
EDO  A2003 (-3.4A)
 1.04A 1k5qA-5hccA:
undetectable
1k5qB-5hccA:
undetectable		 1k5qA-5hccA:
12.93
1k5qB-5hccA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 GLY A1283
GLU A1009
HIS A1002
LEU A1003
PRO A1004
 None
 1.44A 1mjqA-5hccA:
undetectable
1mjqB-5hccA:
undetectable		 1mjqA-5hccA:
7.62
1mjqB-5hccA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 10 GLY A1283
GLU A1009
HIS A1002
LEU A1003
PRO A1004
 None
 1.44A 1mjqG-5hccA:
undetectable
1mjqH-5hccA:
undetectable		 1mjqG-5hccA:
7.62
1mjqH-5hccA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 PRO B 233
PHE B 246
ASN B 245
ASN B 242
 None
 0.96A 1oniG-5hccB:
undetectable
1oniI-5hccB:
undetectable		 1oniG-5hccB:
12.16
1oniI-5hccB:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 LEU A1000
THR A1001
THR A1290
ILE A1294
VAL A1016
 None
 1.25A 1pkvA-5hccA:
undetectable
1pkvB-5hccA:
undetectable		 1pkvA-5hccA:
6.31
1pkvB-5hccA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 VAL A1016
LEU A1000
THR A1001
THR A1290
ILE A1294
 None
 1.27A 1pkvA-5hccA:
undetectable
1pkvB-5hccA:
undetectable		 1pkvA-5hccA:
6.31
1pkvB-5hccA:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 ILE B  87
ALA B  35
PHE B  31
ILE B  39
LEU B 104
 None
 1.00A 1tdrA-5hccB:
undetectable		 1tdrA-5hccB:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 GLN A1463
HIS A1421
HIS A1499
VAL A1068
THR A1287
 None
 1.44A 1ydbA-5hccA:
undetectable		 1ydbA-5hccA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 10 ILE A1381
THR A1383
ILE A1479
LEU A1428
PHE A1477
 None
 1.13A 1z11C-5hccA:
undetectable		 1z11C-5hccA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 10 ILE A1381
THR A1383
ILE A1479
LEU A1428
PHE A1477
 None
 1.11A 1z11D-5hccA:
undetectable		 1z11D-5hccA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 HIS A1030
GLY A 981
GLY A 985
LEU A1356
LEU A1309
 None
 0.95A 1zq9B-5hccA:
undetectable		 1zq9B-5hccA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 SER A1376
LYS A1503
VAL A1374
SER A1411
 None
 1.39A 2j9cA-5hccA:
2.9
2j9cB-5hccA:
3.1
2j9cC-5hccA:
undetectable		 2j9cA-5hccA:
8.01
2j9cB-5hccA:
8.01
2j9cC-5hccA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 GLU A1249
TYR A1143
THR A1148
LEU A1144
TYR A1124
 None
 1.34A 2mjiA-5hccA:
0.9		 2mjiA-5hccA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 5hcc COMPLEMENT C5
COMPLEMENT C5
(Homo
sapiens;
Homo
sapiens) 		4 / 7 LEU B 575
PHE A 788
ILE A 799
GLU A 776
 None
 0.94A 2opxA-5hccB:
undetectable		 2opxA-5hccB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 VAL A1248
THR A1251
VAL A1270
TRP A1273
 None
 1.10A 2p2fA-5hccA:
undetectable		 2p2fA-5hccA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 4 TYR A1024
LEU A 983
LEU A 982
HIS A1030
 None
 1.45A 2x7hB-5hccA:
undetectable		 2x7hB-5hccA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 6 TRP A1077
ASN A1121
SER A1122
ALA A1074
 None
 1.30A 3aruA-5hccA:
undetectable		 3aruA-5hccA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 ASP A1063
SER A1065
SER A1075
GLU A1120
 None
 1.34A 3bc9A-5hccA:
3.4		 3bc9A-5hccA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 LYS A1219
VAL A 942
ILE A1224
TYR A1266
 None
 1.48A 3gvuA-5hccA:
undetectable		 3gvuA-5hccA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 LEU A1000
ILE A 999
HIS A1499
LEU A1078
TYR A1124
 None
 1.05A 3gwxB-5hccA:
undetectable		 3gwxB-5hccA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 ILE B  87
ALA B  35
PHE B  31
ILE B  39
LEU B 104
 None
 1.07A 3ia4D-5hccB:
undetectable		 3ia4D-5hccB:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 10 ASP A1382
PHE A1493
PHE A1377
ILE A1467
LEU A1473
 None
 1.46A 3m0wC-5hccA:
undetectable
3m0wD-5hccA:
undetectable
3m0wE-5hccA:
undetectable
3m0wF-5hccA:
undetectable		 3m0wC-5hccA:
8.32
3m0wD-5hccA:
8.32
3m0wE-5hccA:
8.32
3m0wF-5hccA:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 LEU A1255
ARG A1226
GLY A1296
THR A1298
SER A1301
 None
 1.24A 3okxB-5hccA:
undetectable		 3okxB-5hccA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 GLU A1249
TYR A1124
PHE A1147
LEU A1144
 None
 1.00A 3qeoB-5hccA:
undetectable		 3qeoB-5hccA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		3 / 3 LYS A 974
VAL A1364
HIS A1366
 None
 0.98A 3tj7A-5hccA:
undetectable		 3tj7A-5hccA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 8 GLY A1072
TYR A1124
SER A1073
GLU A1120
 None
 0.78A 3u9hA-5hccA:
undetectable		 3u9hA-5hccA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 8 GLY A1072
TYR A1124
SER A1073
GLU A1120
 None
 0.80A 3u9hB-5hccA:
undetectable		 3u9hB-5hccA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 PHE B 111
VAL B 106
ILE B  54
HIS B 110
VAL B  71
 None
 1.16A 4a97B-5hccB:
undetectable
4a97C-5hccB:
undetectable		 4a97B-5hccB:
19.15
4a97C-5hccB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 8 GLY A1072
TYR A1124
SER A1073
GLU A1120
 None
 0.79A 4bjcA-5hccA:
undetectable		 4bjcA-5hccA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 ILE B 267
ALA B 326
LEU A 752
SER B 337
ILE B 330
 None
 1.32A 4gh8B-5hccB:
undetectable		 4gh8B-5hccB:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 10 ILE B 267
VAL B 299
ILE B 296
VAL B 329
VAL B 327
 None
 1.02A 4j5jB-5hccB:
undetectable		 4j5jB-5hccB:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 VAL A1423
ALA A1422
TYR A1496
TYR A1498
SER A1007
 None
 1.22A 4mm4A-5hccA:
undetectable		 4mm4A-5hccA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 VAL A1423
ALA A1422
TYR A1496
TYR A1498
SER A1007
 None
 1.20A 4mm4B-5hccA:
undetectable		 4mm4B-5hccA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 VAL A1423
ALA A1422
TYR A1496
TYR A1498
SER A1007
 None
 1.23A 4mm6A-5hccA:
undetectable		 4mm6A-5hccA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 VAL A1423
ALA A1422
TYR A1496
TYR A1498
SER A1007
 None
 1.27A 4mm9A-5hccA:
undetectable		 4mm9A-5hccA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 VAL A1423
ALA A1422
TYR A1496
TYR A1498
SER A1007
 None
 1.20A 4mmdB-5hccA:
4.1		 4mmdB-5hccA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 LEU B 502
LEU B 504
VAL B 645
ILE B 526
VAL B 486
 None
 1.11A 4ok1A-5hccB:
undetectable		 4ok1A-5hccB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 5hcc COMPLEMENT C5
COMPLEMENT C5
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG A 766
GLU A1436
TYR B 222
 None
 0.91A 4r29D-5hccA:
undetectable		 4r29D-5hccA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 LEU B 640
LEU B 363
LEU B 424
ALA B 392
PHE B 433
 None
 1.38A 4rtbA-5hccB:
undetectable		 4rtbA-5hccB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 8 SER B 556
ALA B 649
LEU B 648
GLY B 639
 None
 0.97A 4xk8a-5hccB:
undetectable		 4xk8a-5hccB:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 6 ASP A1330
LEU A 982
PHE A1333
ILE A1313
 None
 1.17A 4y4dA-5hccA:
undetectable		 4y4dA-5hccA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		3 / 4 ARG B  32
GLY B  34
GLU B  37
 None
 0.58A 4z2dB-5hccB:
undetectable
4z2dC-5hccB:
undetectable		 4z2dB-5hccB:
21.44
4z2dC-5hccB:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		3 / 3 TYR B 266
THR B 268
THR B 328
 None
 0.59A 5aoxB-5hccB:
undetectable		 5aoxB-5hccB:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		3 / 3 TYR B 266
THR B 268
THR B 328
 None
 0.61A 5aoxE-5hccB:
undetectable		 5aoxE-5hccB:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 11 ALA B 603
LEU B 602
LEU B 571
TYR B 146
HIS B 129
 None
 1.24A 5eb5A-5hccB:
undetectable		 5eb5A-5hccB:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 9 ILE B 128
LEU B 161
THR B 159
ARG B 157
ILE B 183
 None
 1.37A 5ifuB-5hccB:
undetectable		 5ifuB-5hccB:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 4 GLN B 532
VAL B 535
GLU B 564
ILE B 563
 None
 1.44A 5jncA-5hccB:
undetectable		 5jncA-5hccB:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 8 PHE A1600
LEU A1639
ILE A1565
VAL A1563
 None
 0.48A 5nujA-5hccA:
undetectable		 5nujA-5hccA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		5 / 12 ALA B 418
LEU B 354
THR B 359
ARG B 674
THR B 411
 None
 1.14A 5ujxB-5hccB:
undetectable		 5ujxB-5hccB:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.36A 5w97J-5hccA:
undetectable		 5w97J-5hccA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.38A 5x1bJ-5hccA:
undetectable		 5x1bJ-5hccA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.37A 5x1fW-5hccA:
undetectable		 5x1fW-5hccA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5hcc COMPLEMENT C5
COMPLEMENT C5
(Homo
sapiens;
Homo
sapiens) 		5 / 12 LEU B 575
ILE A 799
ILE B 182
TYR B 146
HIS B 129
 None
 1.17A 5y2tB-5hccB:
undetectable		 5y2tB-5hccB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 6 SER A1007
HIS A1421
HIS A1499
TYR A1124
 None
 1.46A 5ycnA-5hccA:
undetectable		 5ycnA-5hccA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 7 PHE B 646
ARG B 539
LEU B 651
GLN B  42
 None
 1.30A 6b89A-5hccB:
undetectable		 6b89A-5hccB:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hcc COMPLEMENT C5
(Homo
sapiens) 		4 / 5 TYR A1326
MET A1328
THR A1329
LEU A1309
 None
 1.38A 6nknJ-5hccA:
undetectable		 6nknJ-5hccA:
5.37