SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5hd9 ENCAPSIDATION
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 THR A 114
GLU A  47
PHE A  42
ILE A  39
 None
 1.26A 2w98B-5hd9A:
2.0		 2w98B-5hd9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 5hd9 ENCAPSIDATION
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 PRO A   9
PHE A   6
LYS A  30
 None
 1.26A 3bjwG-5hd9A:
undetectable		 3bjwG-5hd9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 5hd9 ENCAPSIDATION
PROTEIN
(Bacillus
virus
phi29) 		4 / 4 VAL A  80
TYR A  51
PRO A  38
PHE A  66
 None
 1.24A 3d91B-5hd9A:
undetectable		 3d91B-5hd9A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5hd9 ENCAPSIDATION
PROTEIN
(Bacillus
virus
phi29) 		4 / 6 LEU A 156
LYS A  35
ALA A  33
PRO A  38
 None
 1.29A 3gv1A-5hd9A:
undetectable
3gv1B-5hd9A:
undetectable		 3gv1A-5hd9A:
21.05
3gv1B-5hd9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5hd9 ENCAPSIDATION
PROTEIN
(Bacillus
virus
phi29) 		3 / 3 ASN A 158
ASP A 118
ASP A  68
 None
 0.80A 4obwD-5hd9A:
3.1		 4obwD-5hd9A:
20.70