SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5hdb MONOCLONAL ANTIBODY
10E5 HEAVY CHAIN
(Mus
musculus) 		5 / 11 LEU E  11
GLY E   8
GLU E  10
PRO E 206
HIS E 205
 None
 1.11A 1p91A-5hdbE:
undetectable		 1p91A-5hdbE:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5hdb MONOCLONAL ANTIBODY
10E5 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER E 209
ALA E 204
VAL E 203
 None
 0.61A 4x1iA-5hdbE:
undetectable		 4x1iA-5hdbE:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5hdb MONOCLONAL ANTIBODY
10E5 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER E 209
ALA E 204
VAL E 203
 None
 0.58A 5eypA-5hdbE:
undetectable		 5eypA-5hdbE:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 5hdb MONOCLONAL ANTIBODY
10E5 HEAVY CHAIN
(Mus
musculus) 		5 / 12 THR E  58
ARG E  50
ILE E  70
GLY E  49
ILE E  48
 None
 1.18A 5ifuA-5hdbE:
undetectable		 5ifuA-5hdbE:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5hdb MONOCLONAL ANTIBODY
10E5 HEAVY CHAIN
(Mus
musculus) 		3 / 3 SER E 209
ALA E 204
VAL E 203
 None
 0.52A 5xiwC-5hdbE:
undetectable		 5xiwC-5hdbE:
17.73