SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		3 / 3 VAL A 202
GLU A 284
GLU A 281
 None
 0.74A 2nv4A-5hdeA:
undetectable		 2nv4A-5hdeA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		3 / 3 ASP A  87
TYR A  88
LYS A  55
 None
 1.15A 2othA-5hdeA:
undetectable		 2othA-5hdeA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_GLYA333_0
(CHOLOYLGLYCINE
HYDROLASE)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		3 / 3 ASN A  62
ASN A  90
ARG A 273
 None
 0.70A 2rlcA-5hdeA:
undetectable		 2rlcA-5hdeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		5 / 12 ASN A  58
GLY A  53
VAL A  75
ARG A 273
LEU A  77
 None
 1.35A 3mnoA-5hdeA:
undetectable		 3mnoA-5hdeA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		5 / 12 ASN A  58
GLY A  53
VAL A  75
ARG A 273
LEU A  77
 None
 1.36A 3mnpA-5hdeA:
undetectable		 3mnpA-5hdeA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		5 / 11 ARG A  13
PHE A 260
ILE A 266
TYR A 283
ILE A  11
 None
 1.15A 5hw8A-5hdeA:
undetectable
5hw8D-5hdeA:
undetectable		 5hw8A-5hdeA:
17.15
5hw8D-5hdeA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5hde TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE 12
(Homo
sapiens) 		3 / 3 LYS A  60
ASN A  58
SER A  86
 None
 1.23A 5yw0A-5hdeA:
undetectable		 5yw0A-5hdeA:
22.51