SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hdg HEAT SHOCK FACTOR
PROTEIN 1
(Homo
sapiens) 		3 / 3 PHE A  47
CYH A  36
HIS A  45
 None
 1.13A 3u9fG-5hdgA:
undetectable		 3u9fG-5hdgA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hdg HEAT SHOCK FACTOR
PROTEIN 1
(Homo
sapiens) 		3 / 3 PHE A  47
CYH A  36
HIS A  45
 None
 1.15A 3u9fS-5hdgA:
undetectable		 3u9fS-5hdgA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 5hdg HEAT SHOCK FACTOR
PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  18
ALA A  17
LEU A  73
LEU A  57
PHE A  52
 None
 1.25A 4kykA-5hdgA:
undetectable
4kykB-5hdgA:
undetectable		 4kykA-5hdgA:
19.02
4kykB-5hdgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5hdg HEAT SHOCK FACTOR
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASN A  65
ALA A  67
ARG A  71
 None
 0.39A 5cvtB-5hdgA:
undetectable		 5cvtB-5hdgA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hdg HEAT SHOCK FACTOR
PROTEIN 1
(Homo
sapiens) 		4 / 6 GLN A 100
PHE A  44
LEU A  22
PHE A  18
 None
 1.13A 5zcpP-5hdgA:
undetectable
5zcpW-5hdgA:
undetectable		 5zcpP-5hdgA:
16.73
5zcpW-5hdgA:
16.96