SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)
5hdj NFRA1
(Bacillus
megaterium)
3 / 3 ASP A 113
HIS A  86
ASP A  82
None
0.89A 1nw5A-5hdjA:
undetectable
1nw5A-5hdjA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 GLY A 136
VAL A 145
LEU A 142
LEU A 161
LEU A 149
FMN  A 400 (-3.6A)
None
None
None
None
1.26A 1ya4B-5hdjA:
undetectable
1ya4B-5hdjA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)
5hdj NFRA1
(Bacillus
megaterium)
3 / 3 GLU A  91
HIS A 154
HIS A  84
None
0.89A 3co4A-5hdjA:
undetectable
3co4A-5hdjA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)
5hdj NFRA1
(Bacillus
megaterium)
4 / 7 GLY A  50
PHE A  79
GLY A 160
PHE A 159
None
None
None
FMN  A 400 ( 4.6A)
0.91A 3ko0M-5hdjA:
undetectable
3ko0P-5hdjA:
undetectable
3ko0M-5hdjA:
17.13
3ko0P-5hdjA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)
5hdj NFRA1
(Bacillus
megaterium)
4 / 8 GLY A  50
PHE A  79
GLY A 160
PHE A 159
None
None
None
FMN  A 400 ( 4.6A)
0.95A 3ko0O-5hdjA:
undetectable
3ko0Q-5hdjA:
undetectable
3ko0O-5hdjA:
17.13
3ko0Q-5hdjA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 11 PHE A  77
ALA A 121
ALA A 124
ALA A 125
GLN A  26
None
0.89A 4j6cA-5hdjA:
undetectable
4j6cA-5hdjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 PHE A  77
ALA A 121
ALA A 124
ALA A 125
GLN A  26
None
0.93A 4j6dA-5hdjA:
undetectable
4j6dA-5hdjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 PHE A  77
ALA A 121
ALA A 124
ALA A 125
GLN A  26
None
0.93A 4j6dB-5hdjA:
undetectable
4j6dB-5hdjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 PHE A  77
ALA A 121
ALA A 124
ALA A 125
GLN A  26
None
0.93A 4jbtA-5hdjA:
undetectable
4jbtA-5hdjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 11 PHE A  77
ALA A 121
ALA A 124
ALA A 125
GLN A  26
None
0.92A 4jbtB-5hdjA:
undetectable
4jbtB-5hdjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 PHE A 159
PHE A  77
LEU A  22
GLY A 129
MET A 128
FMN  A 400 ( 4.6A)
None
None
None
None
1.33A 4zjlA-5hdjA:
undetectable
4zjlA-5hdjA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)
5hdj NFRA1
(Bacillus
megaterium)
5 / 12 PRO A 152
LEU A 151
GLY A 245
LEU A 101
CYH A  80
None
1.31A 5emlA-5hdjA:
undetectable
5emlA-5hdjA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)
5hdj NFRA1
(Bacillus
megaterium)
5 / 10 ILE A 156
LEU A 138
LEU A 148
PHE A 240
GLU A 144
None
1.46A 5tixB-5hdjA:
undetectable
5tixB-5hdjA:
22.78