SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5hdl CELL SURFACE PROTEIN
SPAA
(Lactobacillus
rhamnosus) 		4 / 6 GLY A  67
PRO A  72
LYS A  47
THR A  46
 None
 1.04A 2m2oB-5hdlA:
undetectable		 2m2oB-5hdlA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 5hdl CELL SURFACE PROTEIN
SPAA
(Lactobacillus
rhamnosus) 		5 / 12 GLY A 197
GLY A 195
GLU A 194
VAL A 244
THR A 243
 None
 1.07A 2wa2A-5hdlA:
undetectable		 2wa2A-5hdlA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5hdl CELL SURFACE PROTEIN
SPAA
(Lactobacillus
rhamnosus) 		4 / 6 LEU A 210
PHE A 245
LEU A 255
PHE A 258
 None
 1.00A 3abkP-5hdlA:
undetectable
3abkW-5hdlA:
undetectable		 3abkP-5hdlA:
22.39
3abkW-5hdlA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5hdl CELL SURFACE PROTEIN
SPAA
(Lactobacillus
rhamnosus) 		5 / 12 ILE A 200
LEU A 210
ILE A 225
PHE A 284
PHE A 245
 None
 1.08A 3b2rA-5hdlA:
undetectable		 3b2rA-5hdlA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5hdl CELL SURFACE PROTEIN
SPAA
(Lactobacillus
rhamnosus) 		4 / 5 LEU A 210
PHE A 245
LEU A 255
PHE A 258
 None
 0.93A 5x19C-5hdlA:
undetectable
5x19J-5hdlA:
undetectable		 5x19C-5hdlA:
22.39
5x19J-5hdlA:
12.64