SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.47A 2pxcA-5hdmA:
undetectable		 2pxcA-5hdmA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 ARG A 253
PRO A  70
GLY A  69
TRP A  68
 None
 1.29A 2y7kB-5hdmA:
undetectable		 2y7kB-5hdmA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 THR A 168
SER A 183
LYS A 143
 None
 1.16A 3aocC-5hdmA:
1.3		 3aocC-5hdmA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 276
PHE A 120
ALA A 313
VAL A 112
ILE A 115
 None
 1.05A 3e00A-5hdmA:
undetectable		 3e00A-5hdmA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 ILE A 276
PHE A 120
ALA A 313
VAL A 112
ILE A 115
 None
 1.03A 3falA-5hdmA:
undetectable		 3falA-5hdmA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 GLY A 362
PHE A 391
PHE A 387
PHE A 366
 None
 1.13A 3ko0L-5hdmA:
undetectable
3ko0N-5hdmA:
undetectable		 3ko0L-5hdmA:
15.70
3ko0N-5hdmA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLY A 362
PHE A 390
GLY A 365
PHE A 366
 None
 0.95A 3ko0O-5hdmA:
undetectable
3ko0Q-5hdmA:
undetectable		 3ko0O-5hdmA:
15.70
3ko0Q-5hdmA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A 366
GLY A 362
PHE A 391
PHE A 387
 None
 1.10A 3ko0K-5hdmA:
undetectable
3ko0S-5hdmA:
undetectable		 3ko0K-5hdmA:
15.70
3ko0S-5hdmA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 PHE A 366
GLY A 362
PHE A 391
PHE A 387
 None
 1.10A 3ko0R-5hdmA:
undetectable
3ko0T-5hdmA:
undetectable		 3ko0R-5hdmA:
15.70
3ko0T-5hdmA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 ILE A 229
PHE A 245
ASP A 246
GLU A 213
 None
None
PMP  A 500 (-2.8A)
PMP  A 500 (-3.8A)
 1.16A 3kp6A-5hdmA:
undetectable
3kp6B-5hdmA:
undetectable		 3kp6A-5hdmA:
18.30
3kp6B-5hdmA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PHE A 366
PHE A 401
GLY A 365
THR A 411
ILE A 420
 None
 1.29A 3ld6A-5hdmA:
undetectable		 3ld6A-5hdmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 PHE A 366
PHE A 401
GLY A 365
THR A 411
ILE A 420
 None
 1.26A 3ld6B-5hdmA:
undetectable		 3ld6B-5hdmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ASP A  77
ILE A 275
GLY A 317
ILE A 318
ILE A  73
 None
 1.11A 3ndwB-5hdmA:
undetectable		 3ndwB-5hdmA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 9 LEU A 242
GLY A 286
ASP A 246
ILE A 211
GLY A 130
ILE A 244
 None
None
PMP  A 500 (-2.8A)
None
None
None
 1.24A 3nu4B-5hdmA:
undetectable		 3nu4B-5hdmA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.38A 3p97A-5hdmA:
undetectable		 3p97A-5hdmA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.44A 3p97C-5hdmA:
undetectable		 3p97C-5hdmA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A 400
SER A  67
ASP A  57
ILE A  56
 None
 1.03A 3uj7B-5hdmA:
undetectable		 3uj7B-5hdmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 LEU A  44
ALA A  20
PHE A  17
ASN A  29
 None
 1.42A 3uq6A-5hdmA:
undetectable		 3uq6A-5hdmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 THR A 271
GLN A 260
PHE A 252
GLY A 258
ALA A 105
 None
 1.26A 3v3oA-5hdmA:
undetectable		 3v3oA-5hdmA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_2
(PUTATIVE ADENOSINE
KINASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 LEU A  44
ALA A  20
PHE A  17
ASN A  29
 None
 1.38A 3vaqA-5hdmA:
undetectable		 3vaqA-5hdmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.38A 4ctjA-5hdmA:
undetectable		 4ctjA-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.39A 4ctkA-5hdmA:
undetectable		 4ctkA-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLY A  69
GLY A 279
LEU A 280
VAL A 282
 None
 0.81A 4fgzB-5hdmA:
undetectable		 4fgzB-5hdmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 333
ILE A  73
ARG A 323
LEU A 324
ILE A 275
 None
 1.06A 4nx6A-5hdmA:
undetectable		 4nx6A-5hdmA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 333
ILE A  73
ARG A 323
LEU A 324
ILE A 275
 None
 1.08A 4nx7A-5hdmA:
2.3		 4nx7A-5hdmA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A  64
ILE A 420
THR A 423
TYR A 332
 None
 1.41A 4oltB-5hdmA:
undetectable		 4oltB-5hdmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 TYR A 400
PHE A  35
GLY A 388
ILE A 434
 None
 1.00A 4qoiA-5hdmA:
undetectable
4qoiB-5hdmA:
undetectable		 4qoiA-5hdmA:
22.04
4qoiB-5hdmA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB302_1
(CHITOSANASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A  64
ILE A 420
THR A 423
TYR A 332
 None
 1.47A 4qwpB-5hdmA:
0.6		 4qwpB-5hdmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ASP A  63
HIS A  75
LYS A  52
 None
 0.96A 4qzuD-5hdmA:
undetectable		 4qzuD-5hdmA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 LEU A 431
GLY A 343
LEU A 340
ALA A 426
PHE A 364
 None
 1.34A 4wnuC-5hdmA:
undetectable		 4wnuC-5hdmA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.37A 5e9qA-5hdmA:
undetectable		 5e9qA-5hdmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.41A 5e9qC-5hdmA:
undetectable		 5e9qC-5hdmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.38A 5ec8A-5hdmA:
undetectable		 5ec8A-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.42A 5ec8C-5hdmA:
undetectable		 5ec8C-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.38A 5ehgA-5hdmA:
undetectable		 5ehgA-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.38A 5eifA-5hdmA:
undetectable		 5eifA-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.42A 5eifC-5hdmA:
undetectable		 5eifC-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.39A 5ekxB-5hdmA:
undetectable		 5ekxB-5hdmA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.43A 5ikmA-5hdmA:
undetectable		 5ikmA-5hdmA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.43A 5njvA-5hdmA:
undetectable		 5njvA-5hdmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.48A 5njvC-5hdmA:
undetectable		 5njvC-5hdmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 PRO A  70
GLY A 283
GLY A 124
LEU A 280
ALA A 313
 None
None
PMP  A 500 (-3.2A)
None
None
 1.01A 5o96E-5hdmA:
undetectable
5o96F-5hdmA:
undetectable		 5o96E-5hdmA:
20.31
5o96F-5hdmA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 VAL A 118
LEU A 272
PHE A 252
VAL A 112
ILE A 115
 None
 1.21A 5om2A-5hdmA:
undetectable
5om2B-5hdmA:
undetectable		 5om2A-5hdmA:
11.08
5om2B-5hdmA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 GLY A 283
GLY A 317
GLY A 278
GLY A 273
THR A 320
ILE A 318
 None
 1.40A 5wz2B-5hdmA:
undetectable		 5wz2B-5hdmA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 THR A 236
LEU A 232
ILE A 265
PHE A 245
 None
 1.02A 5zsfA-5hdmA:
undetectable
5zsfB-5hdmA:
undetectable		 5zsfA-5hdmA:
10.37
5zsfB-5hdmA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5hdm GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 VAL A 196
ASN A 191
TYR A 190
GLU A 227
 None
 1.30A 6gneB-5hdmA:
undetectable		 6gneB-5hdmA:
22.28