SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.33A 1dsdC-5hdqH:
undetectable		 1dsdC-5hdqH:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR H 117
PRO H 147
THR H 116
PRO H 118
 None
 1.33A 1dsdC-5hdqH:
undetectable		 1dsdC-5hdqH:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 ALA H  12
SER H 172
ARG H  40
LEU H  82
 None
 1.17A 1gahA-5hdqH:
undetectable		 1gahA-5hdqH:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 PRO H 147
VAL H 150
THR H 108
MET H 177
THR H 165
 None
 1.16A 5bykA-5hdqH:
undetectable		 5bykA-5hdqH:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER H 162
SER H 160
SER H 161
SER H 158
 None
 1.39A 5hswA-5hdqH:
undetectable		 5hswA-5hdqH:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 8 TYR H 145
SER H 149
THR H 108
PRO H 167
 None
 1.09A 5jhdE-5hdqH:
18.3
5jhdG-5hdqH:
11.6		 5jhdE-5hdqH:
29.27
5jhdG-5hdqH:
15.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5hdq FAB HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER H 112
ALA H 114
PHE H 146
LEU H 170
 None
 0.29A 5mthA-5hdqH:
30.0		 5mthA-5hdqH:
75.45