SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5he9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5he9 HELICASE LOADER
PHAGE INHIBITOR
PROTEIN
(Staphylococcus
aureus;
Staphylococcus
aureus) 		5 / 12 LEU E  32
LEU E  35
ILE E  22
GLN E  19
THR A 168
 None
None
None
None
ADP  A 401 (-4.3A)
 1.23A 4f4dA-5he9E:
undetectable		 4f4dA-5he9E:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 5he9 HELICASE LOADER
(Staphylococcus
aureus) 		3 / 3 ARG A 187
LYS A 185
LYS A 182
 None
 1.26A 4k50A-5he9A:
undetectable		 4k50A-5he9A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 5he9 HELICASE LOADER
(Staphylococcus
aureus) 		3 / 3 ARG A 187
LYS A 185
LYS A 182
 None
 1.10A 4k50E-5he9A:
undetectable		 4k50E-5he9A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 5he9 HELICASE LOADER
(Staphylococcus
aureus) 		3 / 3 ARG A 187
LYS A 185
LYS A 182
 None
 1.18A 4k50I-5he9A:
undetectable		 4k50I-5he9A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5he9 HELICASE LOADER
(Staphylococcus
aureus) 		5 / 11 ILE A 285
ALA A 283
LEU A 270
ALA A 271
HIS A 246
 None
 1.12A 4nqaA-5he9A:
undetectable		 4nqaA-5he9A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5he9 HELICASE LOADER
(Staphylococcus
aureus) 		5 / 12 GLU A 287
LEU A 270
GLY A 242
GLU A 230
ILE A 227
 None
 1.09A 4xe5A-5he9A:
undetectable		 4xe5A-5he9A:
10.98