SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5hec PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		4 / 8 ASP A  92
SER A 168
ASP A  94
ASP A 230
 None
 0.94A 3havA-5hecA:
undetectable		 3havA-5hecA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5hec PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		3 / 3 SER A 212
TYR A 213
TYR A 214
 None
 0.90A 5lakA-5hecA:
undetectable
5lakI-5hecA:
undetectable		 5lakA-5hecA:
21.27
5lakI-5hecA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5hec PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		3 / 3 SER A 212
TYR A 213
TYR A 214
 None
 0.86A 5lakC-5hecA:
undetectable
5lakJ-5hecA:
undetectable		 5lakC-5hecA:
21.27
5lakJ-5hecA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5hec PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)
(Streptococcus
parasanguinis) 		4 / 6 GLU A  98
PHE A 121
TYR A 214
PHE A 100
 None
 1.43A 5lrbA-5hecA:
2.2		 5lrbA-5hecA:
15.00