SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 5hh0 N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens) 		3 / 3 SER A 125
GLU A 118
ASP A 154
 None
 0.80A 2avdB-5hh0A:
undetectable		 2avdB-5hh0A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5hh0 N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens) 		4 / 7 HIS A 138
ASP A  81
ILE A  77
VAL A  95
 None
 0.87A 3fi0E-5hh0A:
undetectable		 3fi0E-5hh0A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 5hh0 N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens) 		5 / 12 ALA A  56
THR A  58
LEU A  18
THR A  25
GLY A 102
 None
None
None
None
COA  A 201 (-3.2A)
 1.02A 4ypmA-5hh0A:
undetectable		 4ypmA-5hh0A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 5hh0 N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens) 		5 / 9 ILE A  36
MET A  66
VAL A  68
ILE A  46
LEU A 171
 None
 0.99A 5iepA-5hh0A:
undetectable		 5iepA-5hh0A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5hh0 N-ALPHA-ACETYLTRANSF
ERASE 60
(Homo
sapiens) 		5 / 12 LEU A 101
LEU A  99
LEU A 120
ALA A  96
ILE A 135
 COA  A 201 (-4.7A)
None
None
None
None
 1.07A 5mioB-5hh0A:
undetectable		 5mioB-5hh0A:
19.47