SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hh3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 8 LEU A  96
HIS A  93
LEU A 343
LEU A  85
 None
HEM  A 401 (-3.9A)
HEM  A 401 (-4.1A)
HEM  A 401 (-3.9A)
 0.97A 1e7cA-5hh3A:
undetectable		 1e7cA-5hh3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 PHE A 112
LEU A 153
VAL A 229
MET A 230
 None
None
HEM  A 401 ( 3.7A)
None
 0.91A 1hk1A-5hh3A:
undetectable		 1hk1A-5hh3A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 PHE A  84
GLU A 221
GLN A  87
LYS A  75
 None
 1.37A 1l2iB-5hh3A:
undetectable		 1l2iB-5hh3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 7 LEU A  96
PHE A 104
MET A 205
MET A 193
 None
 1.06A 1wrlA-5hh3A:
undetectable
1wrlB-5hh3A:
undetectable		 1wrlA-5hh3A:
13.10
1wrlB-5hh3A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 ALA A 348
LEU A 347
ALA A 148
THR A 147
 HEM  A 401 ( 4.0A)
HEM  A 401 (-4.3A)
None
None
 0.87A 3b6hA-5hh3A:
24.1		 3b6hA-5hh3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 ALA A 348
LEU A 347
ALA A 148
THR A 147
 HEM  A 401 ( 4.0A)
HEM  A 401 (-4.3A)
None
None
 0.87A 3b6hB-5hh3A:
16.3		 3b6hB-5hh3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		5 / 12 GLU A 280
ILE A  57
LEU A  61
GLN A 236
ARG A 239
 None
None
None
HEM  A 401 (-3.9A)
None
 1.49A 4djfB-5hh3A:
undetectable		 4djfB-5hh3A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 PHE A 136
ALA A 245
PRO A 364
LEU A 359
 None
 0.97A 4dtzB-5hh3A:
30.6		 4dtzB-5hh3A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		5 / 12 LEU A 167
ALA A 169
GLU A 173
SER A 170
ARG A 171
 None
 1.31A 4ejwA-5hh3A:
1.1		 4ejwA-5hh3A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		5 / 9 ILE A 356
PHE A 352
VAL A 120
VAL A 237
LEU A 241
 None
 1.09A 4g1bC-5hh3A:
undetectable		 4g1bC-5hh3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		5 / 12 LEU A 163
PHE A 186
GLY A 231
LEU A 153
MET A 190
 None
 1.20A 4ze1A-5hh3A:
26.9		 4ze1A-5hh3A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 6 ARG A 285
HIS A  93
ARG A  97
ILE A 339
 HEM  A 401 (-2.8A)
HEM  A 401 (-3.9A)
GOL  A 402 ( 3.9A)
None
 1.43A 5a06A-5hh3A:
undetectable		 5a06A-5hh3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		3 / 3 THR A 218
ASP A 219
ALA A 220
 None
 0.00A 5g5gB-5hh3A:
undetectable		 5g5gB-5hh3A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		3 / 3 LYS A 281
ASP A 279
ARG A  16
 None
HEM  A 401 ( 4.7A)
None
 1.10A 5jwaA-5hh3A:
undetectable
5jwaH-5hh3A:
undetectable		 5jwaA-5hh3A:
18.79
5jwaH-5hh3A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 5 ASP A 135
GLY A 141
PRO A 138
TRP A 142
 None
 1.33A 5nn8A-5hh3A:
undetectable		 5nn8A-5hh3A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 8 THR A 149
GLN A 115
VAL A 208
GLY A 207
 HEM  A 401 ( 4.7A)
None
None
None
 0.76A 5nzyA-5hh3A:
undetectable		 5nzyA-5hh3A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		3 / 3 GLU A  56
HIS A 296
ARG A 292
 None
 0.88A 5uunA-5hh3A:
undetectable		 5uunA-5hh3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		3 / 3 GLY A 224
VAL A 209
MET A 205
 None
 0.66A 5ycpA-5hh3A:
undetectable		 5ycpA-5hh3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 7 ARG A 171
HIS A 168
VAL A 137
TRP A 142
 None
 1.36A 6g2pA-5hh3A:
undetectable		 6g2pA-5hh3A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 5hh3 OXYA PROTEIN
(Actinoplanes
teichomyceticus) 		4 / 5 LEU A 153
CYH A 150
THR A 146
GLY A 233
 None
None
None
HEM  A 401 (-3.4A)
 1.22A 6gtqA-5hh3A:
undetectable		 6gtqA-5hh3A:
16.25