SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 11 GLU A 167
LEU A 187
ARG A 239
ILE A 208
LEU A 195
 None
 1.21A 1g50C-5hh7A:
undetectable		 1g50C-5hh7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		3 / 3 VAL A 259
TRP A 265
TRP A 256
 None
 1.46A 2xdcC-5hh7A:
undetectable
2xdcD-5hh7A:
undetectable		 2xdcC-5hh7A:
4.31
2xdcD-5hh7A:
4.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		4 / 5 ARG A 306
ARG A 239
GLY A 323
GLU A 182
 None
 1.23A 3k9fA-5hh7A:
undetectable
3k9fB-5hh7A:
undetectable
3k9fC-5hh7A:
undetectable		 3k9fA-5hh7A:
18.56
3k9fB-5hh7A:
18.56
3k9fC-5hh7A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 10 ILE A 252
VAL A 148
TYR A 149
ILE A 299
TRP A 270
 None
 1.40A 3uprA-5hh7A:
undetectable		 3uprA-5hh7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 10 ILE A 252
VAL A 148
TYR A 149
ILE A 299
TRP A 270
 None
 1.37A 3uprC-5hh7A:
undetectable		 3uprC-5hh7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 10 ILE A 252
VAL A 148
TYR A 149
ILE A 299
TRP A 270
 None
 1.36A 5u98A-5hh7A:
undetectable		 5u98A-5hh7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 10 ILE A 252
VAL A 148
TYR A 149
ILE A 299
TRP A 270
 None
 1.39A 5u98D-5hh7A:
undetectable		 5u98D-5hh7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 5hh7 ORIGIN OF
REPLICATION COMPLEX
SUBUNIT 1B
(Arabidopsis
thaliana) 		5 / 12 ASP A 261
GLU A 258
ASP A 298
ASP A 146
ILE A 304
 None
 1.35A 6fzbB-5hh7A:
undetectable		 6fzbB-5hh7A:
15.20