SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		5 / 12 ALA A 217
ILE A 172
MET A 270
LEU A 230
LEU A 212
 None
 1.17A 1dtlA-5hi9A:
undetectable		 1dtlA-5hi9A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 6 ARG A 317
GLU A 309
ASN A 263
ALA A 257
 None
 1.24A 2ejfB-5hi9A:
undetectable		 2ejfB-5hi9A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 8 MET A 255
VAL A 249
THR A 248
THR A 242
 None
 1.24A 2kotB-5hi9A:
undetectable		 2kotB-5hi9A:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		5 / 9 GLY A 278
LEU A 275
TYR A 271
LEU A 253
THR A 248
 None
 1.00A 2npnA-5hi9A:
undetectable		 2npnA-5hi9A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		3 / 3 MET A 372
CYH A 364
PRO A 367
 None
 1.12A 3h52C-5hi9A:
undetectable		 3h52C-5hi9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 7 GLU A 670
TYR A 447
TYR A 515
PHE A 393
 None
 1.33A 3ku9B-5hi9A:
undetectable		 3ku9B-5hi9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 5 LYS A 602
LEU A 600
GLU A 599
LEU A 555
 None
 1.32A 4k4yA-5hi9A:
undetectable		 4k4yA-5hi9A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 4 LYS A 602
LEU A 600
GLU A 599
LEU A 555
 None
 1.34A 4k4yE-5hi9A:
undetectable		 4k4yE-5hi9A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 5 LYS A 602
LEU A 600
GLU A 599
LEU A 555
 None
 1.32A 4k4yI-5hi9A:
undetectable		 4k4yI-5hi9A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 5 HIS A 438
PHE A 407
LEU A 434
PRO A 415
 None
 0.90A 4o8zA-5hi9A:
undetectable		 4o8zA-5hi9A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2
(Rattus
norvegicus) 		4 / 4 GLN A 222
THR A 220
LEU A 230
LEU A 229
 None
 1.30A 5m5kB-5hi9A:
undetectable		 5m5kB-5hi9A:
19.49