SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		3 / 3 TRP C  86
GLU C 178
TYR C 109
 None
 1.23A 2a3aA-5hj3C:
undetectable		 2a3aA-5hj3C:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 5 SER C 167
ARG C 172
GLY C 173
GLU C 112
 None
 1.32A 3k9fA-5hj3C:
undetectable
3k9fB-5hj3C:
undetectable
3k9fC-5hj3C:
undetectable		 3k9fA-5hj3C:
17.26
3k9fB-5hj3C:
17.26
3k9fC-5hj3C:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 7 PHE C 160
PHE C 176
ALA C  82
LEU C 111
 None
 0.86A 4ejgA-5hj3C:
undetectable		 4ejgA-5hj3C:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 8 PHE C 160
PHE C 176
ALA C  82
LEU C 111
 None
 0.93A 4ejgB-5hj3C:
undetectable		 4ejgB-5hj3C:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 7 PHE C 160
PHE C 176
ALA C  82
LEU C 111
 None
 0.89A 4ejgC-5hj3C:
undetectable		 4ejgC-5hj3C:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 5 ARG C 172
GLY C 173
GLU C 112
SER C 167
 None
 1.20A 4z3oA-5hj3C:
undetectable
4z3oB-5hj3C:
undetectable		 4z3oA-5hj3C:
13.10
4z3oB-5hj3C:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 5 SER C 167
ARG C 172
GLY C 173
GLU C 112
 None
 1.03A 5btiA-5hj3C:
undetectable
5btiB-5hj3C:
undetectable		 5btiA-5hj3C:
19.63
5btiB-5hj3C:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 5 SER C 167
ARG C 172
GLY C 173
GLU C 112
 None
 1.05A 5btiC-5hj3C:
undetectable
5btiD-5hj3C:
undetectable		 5btiC-5hj3C:
19.63
5btiD-5hj3C:
18.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		6 / 12 VAL C  66
LEU C  68
GLU C 100
ALA C 101
GLY C 102
LEU C 186
 None
 0.40A 6f6iA-5hj3C:
21.6
6f6iB-5hj3C:
undetectable		 6f6iA-5hj3C:
95.12
6f6iB-5hj3C:
17.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 5hj3 ENVELOPE
GLYCOPROTEIN
(Ebola
virus
sp.) 		4 / 7 LEU C  43
VAL C  66
LEU C 184
LEU C 186
 None
 0.35A 6g9bA-5hj3C:
23.4
6g9bB-5hj3C:
undetectable		 6g9bA-5hj3C:
95.12
6g9bB-5hj3C:
17.13