SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hjc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		6 / 7 TRP A 332
PRO A 333
LEU A 343
LEU A 345
ASN A 391
MET A 400
 None
 0.58A 3u5jA-5hjcA:
17.9		 3u5jA-5hjcA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		7 / 8 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
MET A 400
 None
 0.61A 3u5kA-5hjcA:
17.9		 3u5kA-5hjcA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		6 / 7 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
 None
 0.58A 3u5kB-5hjcA:
18.0		 3u5kB-5hjcA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		7 / 8 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
MET A 400
 None
 0.65A 3u5kC-5hjcA:
17.9		 3u5kC-5hjcA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		7 / 8 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
MET A 400
 None
 0.75A 3u5kD-5hjcA:
18.0		 3u5kD-5hjcA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		4 / 5 VAL A 338
LEU A 343
LEU A 345
ASN A 391
 None
 0.34A 4a9jA-5hjcA:
19.2		 4a9jA-5hjcA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		4 / 5 VAL A 338
LEU A 343
LEU A 345
ASN A 391
 None
 0.37A 4a9jB-5hjcA:
19.3		 4a9jB-5hjcA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		4 / 5 VAL A 338
LEU A 343
LEU A 345
ASN A 391
 None
 0.38A 4a9jC-5hjcA:
19.2		 4a9jC-5hjcA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		5 / 6 VAL A 338
LEU A 343
TYR A 390
ASN A 391
VAL A 397
 None
 0.52A 4a9kA-5hjcA:
18.0		 4a9kA-5hjcA:
37.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		4 / 5 VAL A 338
LEU A 343
ASN A 391
VAL A 397
 None
 0.69A 4a9kB-5hjcA:
18.2		 4a9kB-5hjcA:
37.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		7 / 9 TRP A 332
PRO A 333
VAL A 338
LEU A 343
LEU A 345
ASN A 391
MET A 400
 None
 0.56A 4c66A-5hjcA:
18.0		 4c66A-5hjcA:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		4 / 6 PRO A 333
VAL A 338
TYR A 348
ASN A 391
 None
 0.78A 5pbeA-5hjcA:
16.8		 5pbeA-5hjcA:
29.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5hjc BROMODOMAIN-CONTAINI
NG PROTEIN 3
(Homo
sapiens) 		7 / 8 PRO A 333
VAL A 338
LEU A 343
LEU A 345
CYH A 387
TYR A 390
ASN A 391
 None
 0.53A 5y1yA-5hjcA:
18.1		 5y1yA-5hjcA:
39.29