SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG2_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 TRP A 337
ASN A 339
VAL A 321
PRO A 322
 None
 1.30A 1rg2A-5hjrA:
0.0		 1rg2A-5hjrA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RGU_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 TRP A 337
ASN A 339
VAL A 321
PRO A 322
 None
 1.34A 1rguA-5hjrA:
1.6		 1rguA-5hjrA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 7 PHE A 825
VAL A 787
GLY A 786
ASP A 800
 None
 0.86A 1t88A-5hjrA:
undetectable		 1t88A-5hjrA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 7 HIS A 698
PHE A 673
ILE A 488
TRP A 423
 5GF  A1021 (-4.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.1A)
 1.22A 1tdnA-5hjrA:
undetectable		 1tdnA-5hjrA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 7 PHE A 825
VAL A 787
GLY A 786
ASP A 800
 None
 0.96A 2a1mA-5hjrA:
undetectable		 2a1mA-5hjrA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 8 PHE A 825
VAL A 787
GLY A 786
ASP A 800
 None
 0.91A 2a1oA-5hjrA:
undetectable		 2a1oA-5hjrA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 265
GLU A 250
ASP A  42
 None
FMT  A1017 (-4.2A)
None
 0.88A 2avdB-5hjrA:
undetectable		 2avdB-5hjrA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 ALA A 773
ASP A 772
TRP A 798
ARG A 834
 None
None
None
FMT  A1022 (-3.6A)
 1.45A 2ouzA-5hjrA:
undetectable		 2ouzA-5hjrA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 8 LEU A 288
PRO A 746
SER A 664
VAL A 394
 None
 1.19A 2qd2A-5hjrA:
undetectable		 2qd2A-5hjrA:
17.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.35A 2qmjA-5hjrA:
43.0		 2qmjA-5hjrA:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ILE A 488
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.34A 2qmjA-5hjrA:
43.0		 2qmjA-5hjrA:
30.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 TRP A 562
MET A 565
TRP A 637
THR A 642
 5GF  A1021 (-4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
None
 0.39A 2qmjA-5hjrA:
43.1		 2qmjA-5hjrA:
30.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		6 / 12 ASP A 305
ASP A 451
ASP A 564
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.47A 2x2iA-5hjrA:
36.1		 2x2iA-5hjrA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 TRP A 562
MET A 565
ARG A 624
TRP A 637
 5GF  A1021 (-4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
 0.63A 2x2iA-5hjrA:
36.1		 2x2iA-5hjrA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ASP A 564
MET A 565
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.50A 2x2iB-5hjrA:
33.7		 2x2iB-5hjrA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ASP A 564
MET A 565
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.42A 2x2iC-5hjrA:
36.1		 2x2iC-5hjrA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ASP A 564
MET A 565
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.43A 2x2iD-5hjrA:
33.5		 2x2iD-5hjrA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ILE A 776
LEU A 770
ILE A 822
VAL A 670
PHE A 695
 None
 1.08A 2ygpA-5hjrA:
undetectable		 2ygpA-5hjrA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 LEU A 304
GLU A 575
ARG A 300
ALA A 341
SER A 381
 EDO  A1005 (-3.8A)
EDO  A1005 ( 4.9A)
EDO  A1005 (-4.1A)
None
None
 1.22A 3apvA-5hjrA:
undetectable		 3apvA-5hjrA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 VAL A 621
VAL A 447
TYR A 418
VAL A 601
THR A 605
 None
 1.18A 3dl9A-5hjrA:
undetectable		 3dl9A-5hjrA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 ASN A 536
HIS A 584
VAL A 583
 None
 0.87A 3elzB-5hjrA:
2.0		 3elzB-5hjrA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 7 LEU A 168
GLN A  92
LEU A  78
LEU A 268
 None
 0.79A 3g8iA-5hjrA:
undetectable		 3g8iA-5hjrA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 GLY A  93
THR A 125
ILE A 149
ASP A  72
ARG A 127
 None
 1.30A 3iv6B-5hjrA:
undetectable		 3iv6B-5hjrA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 GLY A  93
THR A 125
ILE A 149
LEU A 128
ARG A 127
 None
 1.34A 3iv6B-5hjrA:
undetectable		 3iv6B-5hjrA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 THR A 735
SER A 842
ASP A 847
ILE A 909
LEU A 868
 FMT  A1016 ( 3.7A)
None
None
None
None
 1.24A 3iv6D-5hjrA:
undetectable		 3iv6D-5hjrA:
15.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 564
MET A 565
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.65A 3l4wA-5hjrA:
42.8		 3l4wA-5hjrA:
30.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 562
ASP A 564
MET A 565
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.46A 3l4wA-5hjrA:
42.8		 3l4wA-5hjrA:
30.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 HIS A 647
TYR A 309
ILE A 650
SER A 657
LEU A 658
 None
EDO  A1006 (-4.2A)
None
None
None
 1.00A 3n8xA-5hjrA:
undetectable		 3n8xA-5hjrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 ASP A 305
ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 564
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.46A 3phaA-5hjrA:
36.6		 3phaA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 490
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 ( 4.6A)
 1.22A 3phaA-5hjrA:
36.6		 3phaA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.50A 3phaA-5hjrA:
36.6		 3phaA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.40A 3phaB-5hjrA:
41.7		 3phaB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 488
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.25A 3phaB-5hjrA:
41.7		 3phaB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 490
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 ( 4.6A)
 1.20A 3phaB-5hjrA:
41.7		 3phaB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.42A 3phaB-5hjrA:
41.7		 3phaB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 490
ILE A 488
ILE A 452
ASP A 305
 5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
None
5GF  A1021 (-3.6A)
None
 1.30A 3phaB-5hjrA:
41.7		 3phaB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 452
TRP A 525
ASP A 564
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.41A 3phaC-5hjrA:
41.2		 3phaC-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 488
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.18A 3phaC-5hjrA:
41.2		 3phaC-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.50A 3phaC-5hjrA:
41.2		 3phaC-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 452
TRP A 525
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.33A 3phaD-5hjrA:
41.5		 3phaD-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 488
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.19A 3phaD-5hjrA:
41.5		 3phaD-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.45A 3phaD-5hjrA:
41.5		 3phaD-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 451
ILE A 488
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.24A 3pocA-5hjrA:
41.2		 3pocA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 525
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.48A 3pocA-5hjrA:
41.2		 3pocA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.89A 3pocA-5hjrA:
41.2		 3pocA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 451
ILE A 488
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.25A 3pocB-5hjrA:
42.9		 3pocB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 525
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.49A 3pocB-5hjrA:
42.9		 3pocB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.92A 3pocB-5hjrA:
42.9		 3pocB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 ASP A 305
ASP A 451
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
PHE A 674
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.0A)
 0.48A 3topA-5hjrA:
41.9		 3topA-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 305
TRP A 525
MET A 565
ASP A 640
PHE A 673
 None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
 1.36A 3topA-5hjrA:
41.9		 3topA-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.45A 3topA-5hjrA:
41.9		 3topA-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 ILE A 452
TRP A 562
TRP A 637
THR A 642
 5GF  A1021 (-3.6A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
None
 0.38A 3topA-5hjrA:
41.9		 3topA-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.47A 3topB-5hjrA:
41.9		 3topB-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 640
ASP A 305
ARG A 624
ASP A 564
HIS A 492
 5GF  A1021 (-2.6A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.1A)
None
 1.43A 3topB-5hjrA:
41.9		 3topB-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 ILE A 452
TRP A 562
TRP A 637
PHE A 674
 5GF  A1021 (-3.6A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
None
 0.35A 3topB-5hjrA:
41.9		 3topB-5hjrA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 ARG A  51
GLU A 294
THR A 293
 None
None
FMT  A1007 (-3.5A)
 0.92A 3v4tA-5hjrA:
undetectable		 3v4tA-5hjrA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 MET A 748
GLN A 687
PRO A 778
TYR A 691
 None
 1.32A 3vkxA-5hjrA:
undetectable		 3vkxA-5hjrA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 452
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.46A 3w37A-5hjrA:
41.2		 3w37A-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 488
TRP A 562
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.27A 3w37A-5hjrA:
41.2		 3w37A-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 305
TRP A 423
ASP A 640
PHE A 674
HIS A 700
 None
5GF  A1021 (-3.1A)
5GF  A1021 (-2.6A)
None
FMT  A1020 (-3.9A)
 1.46A 3w37A-5hjrA:
41.2		 3w37A-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W37_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 TRP A 423
ILE A 452
TRP A 525
TRP A 637
 5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
5GF  A1021 (-3.7A)
5GF  A1021 ( 4.6A)
 0.39A 3w37A-5hjrA:
41.2		 3w37A-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ILE A 452
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.45A 3welA-5hjrA:
41.1		 3welA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 305
ASP A 451
ILE A 488
TRP A 562
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.28A 3welA-5hjrA:
41.1		 3welA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 6 TRP A 423
ILE A 452
TRP A 525
MET A 565
TRP A 637
 5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
5GF  A1021 (-3.7A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
 0.35A 3welA-5hjrA:
41.2		 3welA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 305
ASP A 451
ILE A 452
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.31A 3wemA-5hjrA:
40.9		 3wemA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 488
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.28A 3wemA-5hjrA:
40.9		 3wemA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 TRP A 423
TRP A 525
TRP A 562
TRP A 637
 5GF  A1021 (-3.1A)
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
 0.54A 3wemA-5hjrA:
40.9		 3wemA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 452
TRP A 562
ASP A 564
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.31A 3wenA-5hjrA:
40.9		 3wenA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ASP A 451
ILE A 488
MET A 565
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.29A 3wenA-5hjrA:
40.9		 3wenA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 305
TRP A 423
ASP A 640
PHE A 674
HIS A 700
 None
5GF  A1021 (-3.1A)
5GF  A1021 (-2.6A)
None
FMT  A1020 (-3.9A)
 1.44A 3wenA-5hjrA:
40.9		 3wenA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 305
ASP A 451
ILE A 452
TRP A 562
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.26A 3weoA-5hjrA:
50.2		 3weoA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ASP A 451
ILE A 488
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.30A 3weoA-5hjrA:
50.2		 3weoA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 6 TRP A 423
ILE A 488
TRP A 525
MET A 565
TRP A 637
 5GF  A1021 (-3.1A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
 0.43A 3weoA-5hjrA:
50.1		 3weoA-5hjrA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 451
ILE A 452
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.35A 4b9zA-5hjrA:
38.0		 4b9zA-5hjrA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 451
ILE A 488
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.30A 4b9zA-5hjrA:
38.0		 4b9zA-5hjrA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 451
ILE A 488
ASP A 564
GLU A 567
ARG A 624
ASP A 640
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
None
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-4.0A)
 1.50A 4b9zA-5hjrA:
38.0		 4b9zA-5hjrA:
27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 ASP A 870
ARG A 482
THR A 873
 None
 0.85A 4i13A-5hjrA:
undetectable		 4i13A-5hjrA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 8 ARG A 827
GLN A 859
GLY A 860
THR A 861
 None
 1.01A 4k87A-5hjrA:
undetectable		 4k87A-5hjrA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.95A 4k8cA-5hjrA:
undetectable		 4k8cA-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.95A 4kahA-5hjrA:
undetectable		 4kahA-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.94A 4kahB-5hjrA:
undetectable		 4kahB-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.95A 4kanB-5hjrA:
undetectable		 4kanB-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.94A 4kbeA-5hjrA:
undetectable		 4kbeA-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.92A 4kbeB-5hjrA:
undetectable		 4kbeB-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 7 LEU A 288
PRO A 746
SER A 664
VAL A 394
 None
 1.27A 4klrA-5hjrA:
undetectable		 4klrA-5hjrA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.95A 4lbgA-5hjrA:
undetectable		 4lbgA-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 SER A 530
TYR A 511
PRO A 526
 None
 0.96A 4lbgB-5hjrA:
undetectable		 4lbgB-5hjrA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUF_A_ACTA605_0
(SERUM ALBUMIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 4 ALA A 635
HIS A 419
PHE A 620
LEU A 416
 None
 1.37A 4lufA-5hjrA:
undetectable		 4lufA-5hjrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 ASP A 564
ASN A 566
ALA A 625
ASP A 640
 5GF  A1021 (-2.1A)
None
None
5GF  A1021 (-2.6A)
 1.20A 4mdbA-5hjrA:
undetectable		 4mdbA-5hjrA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 10 ASP A 843
TYR A 734
SER A 841
GLY A 417
ASP A 869
 None
 1.46A 4mm7A-5hjrA:
undetectable		 4mm7A-5hjrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 MET A 748
VAL A 747
MET A 688
ILE A 822
VAL A 824
 None
 1.33A 4okwA-5hjrA:
undetectable		 4okwA-5hjrA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 ASP A 870
ARG A 482
THR A 873
 None
 0.86A 4p3rA-5hjrA:
undetectable		 4p3rA-5hjrA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 11 HIS A 477
LEU A 475
ALA A 479
VAL A 431
LEU A 432
 None
 1.04A 4p65C-5hjrA:
undetectable
4p65D-5hjrA:
undetectable
4p65J-5hjrA:
undetectable
4p65L-5hjrA:
undetectable		 4p65C-5hjrA:
2.59
4p65D-5hjrA:
3.31
4p65J-5hjrA:
3.31
4p65L-5hjrA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 11 LEU A 151
HIS A  77
LEU A  89
ALA A  62
LEU A  64
 None
 0.93A 4p65E-5hjrA:
undetectable
4p65F-5hjrA:
undetectable
4p65J-5hjrA:
undetectable
4p65L-5hjrA:
undetectable		 4p65E-5hjrA:
2.59
4p65F-5hjrA:
3.31
4p65J-5hjrA:
3.31
4p65L-5hjrA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 11 LEU A  64
LEU A 151
HIS A  77
LEU A  89
ALA A  62
 None
 1.03A 4p65B-5hjrA:
undetectable
4p65D-5hjrA:
undetectable
4p65G-5hjrA:
undetectable
4p65H-5hjrA:
undetectable		 4p65B-5hjrA:
3.31
4p65D-5hjrA:
3.31
4p65G-5hjrA:
2.59
4p65H-5hjrA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 ASP A 490
TYR A 460
TRP A 562
 5GF  A1021 ( 4.6A)
None
5GF  A1021 (-4.6A)
 1.25A 4p7nA-5hjrA:
6.8		 4p7nA-5hjrA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_C_ACTC407_0
(PROTON-GATED ION
CHANNEL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 4 ILE A 822
ILE A 801
ARG A 834
TYR A 691
 None
FMT  A1022 ( 4.4A)
FMT  A1022 (-3.6A)
None
 1.07A 4zzcC-5hjrA:
undetectable		 4zzcC-5hjrA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_D_ACTD406_0
(PROTON-GATED ION
CHANNEL)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 4 ILE A 822
ILE A 801
ARG A 834
TYR A 691
 None
FMT  A1022 ( 4.4A)
FMT  A1022 (-3.6A)
None
 1.05A 4zzcD-5hjrA:
0.6		 4zzcD-5hjrA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 GLU A 380
TRP A 344
ASN A 595
 None
 1.05A 5dv4A-5hjrA:
undetectable		 5dv4A-5hjrA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 PRO A 693
LEU A 622
SER A 664
 None
 0.65A 5fsaB-5hjrA:
undetectable		 5fsaB-5hjrA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 8 GLY A 437
TYR A 425
ASP A 430
ARG A 426
 None
 0.75A 5gqbA-5hjrA:
2.7		 5gqbA-5hjrA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ALA A 862
GLY A 860
SER A 892
GLY A 828
LEU A 852
 None
 1.01A 5gwxA-5hjrA:
undetectable		 5gwxA-5hjrA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ALA A 862
LEU A 852
SER A 962
ILE A 963
LEU A 950
 None
 1.07A 5hi6A-5hjrA:
undetectable		 5hi6A-5hjrA:
11.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 562
ASP A 564
MET A 565
PHE A 571
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.31A 5iefA-5hjrA:
61.4		 5iefA-5hjrA:
93.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 4 ARG A 624
TRP A 637
ASP A 669
ARG A 696
 5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 ( 4.6A)
None
 0.22A 5iefA-5hjrA:
61.4		 5iefA-5hjrA:
93.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 VAL A 266
THR A  99
ARG A 100
GLN A  92
LEU A  89
 None
 1.44A 5m54B-5hjrA:
undetectable		 5m54B-5hjrA:
20.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 TRP A 423
ASP A 451
ILE A 488
TRP A 525
TRP A 562
ASP A 564
MET A 565
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.80A 5nn6A-5hjrA:
42.3		 5nn6A-5hjrA:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 TRP A 423
ASP A 451
ILE A 488
TRP A 562
ASP A 564
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
None
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.47A 5nn6A-5hjrA:
42.3		 5nn6A-5hjrA:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 305
ASP A 451
ILE A 452
ASP A 640
PHE A 673
 None
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
 1.50A 5nn8A-5hjrA:
30.7		 5nn8A-5hjrA:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ASP A 451
ILE A 488
TRP A 525
TRP A 562
ASP A 564
ARG A 624
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.0A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.41A 5nn8A-5hjrA:
30.7		 5nn8A-5hjrA:
32.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 ASP A 305
ASP A 669
ASP A 640
ASP A 564
HIS A 698
 None
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-4.0A)
 1.41A 5nn8A-5hjrA:
30.7		 5nn8A-5hjrA:
32.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 10 TRP A 562
ASP A 564
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-4.6A)
5GF  A1021 (-2.1A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.55A 5x7pA-5hjrA:
34.4		 5x7pA-5hjrA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 6 PRO A 444
TYR A 418
LEU A 730
VAL A 838
 None
 0.86A 5x80A-5hjrA:
undetectable
5x80B-5hjrA:
undetectable		 5x80A-5hjrA:
11.40
5x80B-5hjrA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		3 / 3 TYR A 279
HIS A 277
MET A 275
 None
 1.12A 6af6A-5hjrA:
undetectable		 6af6A-5hjrA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ILE A 488
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.07A 6c9xA-5hjrA:
36.7		 6c9xA-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 ASP A 305
TRP A 423
ILE A 452
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.53A 6c9xA-5hjrA:
36.7		 6c9xA-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 TRP A 423
ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.94A 6c9xA-5hjrA:
36.7		 6c9xA-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 305
ILE A 488
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.07A 6c9xB-5hjrA:
36.6		 6c9xB-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 ASP A 305
TRP A 423
ILE A 452
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.54A 6c9xB-5hjrA:
36.6		 6c9xB-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 TRP A 423
ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.94A 6c9xB-5hjrA:
36.6		 6c9xB-5hjrA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ILE A 452
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.46A 6c9zA-5hjrA:
35.4		 6c9zA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.98A 6c9zA-5hjrA:
35.4		 6c9zA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ILE A 488
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 None
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.02A 6c9zA-5hjrA:
35.4		 6c9zA-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 305
ILE A 452
ILE A 488
TRP A 525
ASP A 564
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.47A 6c9zB-5hjrA:
36.5		 6c9zB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 305
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
PHE A 673
HIS A 698
 None
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.08A 6c9zB-5hjrA:
36.5		 6c9zB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ILE A 452
ILE A 488
TRP A 525
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.97A 6c9zB-5hjrA:
36.5		 6c9zB-5hjrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 451
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.20A 6ca1A-5hjrA:
41.1		 6ca1A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.53A 6ca1A-5hjrA:
41.1		 6ca1A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.87A 6ca1A-5hjrA:
41.1		 6ca1A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 451
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.21A 6ca1B-5hjrA:
39.8		 6ca1B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		11 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.48A 6ca1B-5hjrA:
39.8		 6ca1B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 TRP A 423
ASP A 451
ILE A 452
ILE A 488
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-3.1A)
5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.85A 6ca1B-5hjrA:
39.8		 6ca1B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 451
ILE A 452
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.50A 6ca3A-5hjrA:
36.2		 6ca3A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.94A 6ca3A-5hjrA:
36.2		 6ca3A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 451
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.19A 6ca3A-5hjrA:
36.2		 6ca3A-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		10 / 12 ASP A 451
ILE A 452
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.51A 6ca3B-5hjrA:
35.4		 6ca3B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		8 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 525
ASP A 564
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-3.7A)
5GF  A1021 (-2.1A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.81A 6ca3B-5hjrA:
35.4		 6ca3B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		7 / 12 ASP A 451
ILE A 452
ILE A 488
TRP A 562
TRP A 637
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
5GF  A1021 (-3.6A)
None
5GF  A1021 (-4.6A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 0.94A 6ca3B-5hjrA:
35.4		 6ca3B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		9 / 12 ASP A 451
ILE A 488
ASP A 564
MET A 565
ARG A 624
TRP A 637
ASP A 640
PHE A 673
HIS A 698
 5GF  A1021 (-2.0A)
None
5GF  A1021 (-2.1A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.4A)
5GF  A1021 ( 4.6A)
5GF  A1021 (-2.6A)
5GF  A1021 (-3.6A)
5GF  A1021 (-4.0A)
 1.20A 6ca3B-5hjrA:
35.4		 6ca3B-5hjrA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		4 / 5 PHE A 571
PRO A 568
MET A 565
VAL A 576
 None
None
5GF  A1021 (-2.6A)
None
 1.33A 6ekzA-5hjrA:
undetectable		 6ekzA-5hjrA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5hjr NEUTRAL
ALPHA-GLUCOSIDASE AB
(Mus
musculus) 		5 / 12 GLY A 598
HIS A 602
PRO A 123
VAL A 636
GLY A 319
 None
 1.27A 6gngA-5hjrA:
undetectable		 6gngA-5hjrA:
20.73