SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5hjz ENDORIBONUCLEASE
MAZF9
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  46
VAL A  10
ILE A   7
LEU A  65
VAL A  63
 None
 1.19A 3w67C-5hjzA:
undetectable		 3w67C-5hjzA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 5hjz ENDORIBONUCLEASE
MAZF9
(Mycobacterium
tuberculosis) 		5 / 12 GLU A  81
LEU A  12
ARG A  84
ALA A  15
GLU A  19
 U  C   4 ( 3.8A)
None
None
None
None
 1.36A 4cpzB-5hjzA:
undetectable		 4cpzB-5hjzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 5hjz ENDORIBONUCLEASE
MAZF9
(Mycobacterium
tuberculosis) 		5 / 12 GLU A  81
LEU A  12
ARG A  84
ALA A  15
GLU A  19
 U  C   4 ( 3.8A)
None
None
None
None
 1.42A 4cpzD-5hjzA:
undetectable		 4cpzD-5hjzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 5hjz ENDORIBONUCLEASE
MAZF9
(Mycobacterium
tuberculosis) 		5 / 12 GLU A  81
LEU A  12
ARG A  84
ALA A  15
GLU A  19
 U  C   4 ( 3.8A)
None
None
None
None
 1.38A 4cpzE-5hjzA:
undetectable		 4cpzE-5hjzA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 5hjz ENDORIBONUCLEASE
MAZF9
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  63
LEU A 103
LEU A 110
ILE A  83
ALA A  80
 None
 1.42A 5xprA-5hjzA:
undetectable		 5xprA-5hjzA:
15.37