SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P6K_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	5hlj	VP24 (White spot syndrome virus)	4 / 5	GLY A 81 GLN A 82 VAL A 65 SER A 100	None	1.38A	1p6kB-5hljA: undetectable	1p6kB-5hljA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS6_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	5hlj	VP24 (White spot syndrome virus)	4 / 5	GLY A 81 GLN A 82 VAL A 65 SER A 100	None	1.37A	1rs6B-5hljA: undetectable	1rs6B-5hljA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZZU_B_ACTB861_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	5hlj	VP24 (White spot syndrome virus)	4 / 5	GLY A 81 GLN A 82 VAL A 65 SER A 100	None	1.39A	1zzuB-5hljA: undetectable	1zzuB-5hljA: 17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5hlj	VP24 (White spot syndrome virus)	4 / 6	ILE A 183 LEU A 119 PHE A 179 THR A 52	None	1.06A	5b1aN-5hljA: undetectable 5b1aW-5hljA: undetectable	5b1aN-5hljA: 17.00 5b1aW-5hljA: 19.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P6K_B_ACTB861_0","NITRIC-OXIDE SYNTHASE, BRAIN","5hlj","VP24","White spot syndrome virus",4,"GLY A  81;GLN A  82;VAL A  65;SER A 100","None","1.38A","1p6kB-5hljA:undetectable","1p6kB-5hljA:19.90"],["1RS6_B_ACTB861_0","NITRIC-OXIDE SYNTHASE, BRAIN","5hlj","VP24","White spot syndrome virus",4,"GLY A  81;GLN A  82;VAL A  65;SER A 100","None","1.37A","1rs6B-5hljA:undetectable","1rs6B-5hljA:19.90"],["1ZZU_B_ACTB861_0","NITRIC-OXIDE SYNTHASE, BRAIN","5hlj","VP24","White spot syndrome virus",4,"GLY A  81;GLN A  82;VAL A  65;SER A 100","None","1.39A","1zzuB-5hljA:undetectable","1zzuB-5hljA:17.38"],["5B1A_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5hlj","VP24","White spot syndrome virus",4,"ILE A 183;LEU A 119;PHE A 179;THR A  52","None","1.06A","5b1aN-5hljA:undetectable;5b1aW-5hljA:undetectable","5b1aN-5hljA:17.00;5b1aW-5hljA:19.21"]]