SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hly'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5hly INHIBIN BETA A CHAIN
(Homo
sapiens) 		5 / 12 HIS A 289
VAL A 211
PHE A 221
VAL A 171
LEU A 254
 None
 1.17A 1cilA-5hlyA:
undetectable		 1cilA-5hlyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5hly INHIBIN BETA A CHAIN
(Homo
sapiens) 		3 / 3 LYS A 160
VAL A 255
HIS A 289
 None
 1.13A 3tj7A-5hlyA:
undetectable		 3tj7A-5hlyA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 5hly INHIBIN BETA A CHAIN
(Homo
sapiens) 		4 / 8 MET A 399
MET A 401
LEU A  66
HIS A  67
 None
 0.97A 4ok1A-5hlyA:
undetectable		 4ok1A-5hlyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5hly INHIBIN BETA A CHAIN
(Homo
sapiens) 		4 / 6 LYS A 134
ASP A 239
PRO A 291
LEU A 157
 None
 1.37A 5bmvB-5hlyA:
undetectable		 5bmvB-5hlyA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5hly INHIBIN BETA A CHAIN
(Homo
sapiens) 		4 / 6 ARG A 229
LEU A 231
ALA A 297
GLN A 233
 None
 1.01A 6b89B-5hlyA:
undetectable		 6b89B-5hlyA:
14.81