SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hlz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5hlz INHIBIN BETA A CHAIN
(Homo
sapiens) 		5 / 12 HIS A 289
VAL A 211
PHE A 221
VAL A 171
LEU A 254
 None
 1.18A 1cilA-5hlzA:
undetectable		 1cilA-5hlzA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 5hlz INHIBIN BETA A CHAIN
(Homo
sapiens) 		5 / 12 GLY A 258
LYS A 134
ILE A 242
SER A 253
LEU A 254
 None
 1.01A 1v2xA-5hlzA:
undetectable		 1v2xA-5hlzA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 5hlz INHIBIN BETA A CHAIN
(Homo
sapiens) 		3 / 3 LYS A 160
VAL A 255
HIS A 289
 None
 1.17A 3tj7A-5hlzA:
undetectable		 3tj7A-5hlzA:
23.60