SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 4 ALA A  59
VAL A  42
ALA A  41
HIS A 119
 None
 0.79A 1q23A-5hm9A:
undetectable		 1q23A-5hm9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		3 / 3 VAL A  42
ALA A  41
HIS A 119
 None
 0.53A 1q23G-5hm9A:
undetectable		 1q23G-5hm9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		3 / 3 VAL A  42
ALA A  41
HIS A 119
 None
 0.63A 1q23L-5hm9A:
undetectable		 1q23L-5hm9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		3 / 3 VAL A  42
ALA A  41
HIS A 119
 None
 0.51A 1q23J-5hm9A:
undetectable		 1q23J-5hm9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 4 GLY A  44
GLY A  58
THR A  69
LEU A 109
 None
 0.94A 3si7C-5hm9A:
undetectable
3si7D-5hm9A:
undetectable		 3si7C-5hm9A:
18.40
3si7D-5hm9A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 7 ILE A 216
LEU A 108
MET A 111
GLY A  65
 None
 0.98A 4hbfA-5hm9A:
undetectable		 4hbfA-5hm9A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 7 ILE A 216
LEU A 108
MET A 111
GLY A  65
 None
 0.93A 4hc3A-5hm9A:
undetectable		 4hc3A-5hm9A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		5 / 12 ALA A 174
SER A 172
ILE A  68
ALA A  59
GLY A 183
 None
 1.12A 4r29D-5hm9A:
undetectable		 4r29D-5hm9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 6 PHE A 137
VAL A 186
ALA A 136
THR A 210
 None
 1.09A 5t7bA-5hm9A:
undetectable		 5t7bA-5hm9A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 7 ALA A 107
THR A  69
GLN A  96
VAL A  97
 None
 0.97A 6cduA-5hm9A:
undetectable
6cduE-5hm9A:
undetectable		 6cduA-5hm9A:
20.00
6cduE-5hm9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		4 / 7 GLN A  96
VAL A  97
ALA A 107
THR A  69
 None
 0.96A 6cduH-5hm9A:
undetectable
6cduI-5hm9A:
undetectable		 6cduH-5hm9A:
20.00
6cduI-5hm9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		5 / 10 VAL A  67
LEU A 108
GLY A 183
GLY A  46
VAL A  82
 None
 1.13A 6eu9B-5hm9A:
undetectable		 6eu9B-5hm9A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5hm9 MAMO PROTEASE DOMAIN
(Magnetospirillum
magneticum) 		5 / 12 ILE A 166
VAL A 211
THR A 210
ILE A 197
PRO A 130
 None
 1.09A 6hlpA-5hm9A:
undetectable		 6hlpA-5hm9A:
16.13