SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5hmb AZI13
(Streptomyces
sahachiroi) 		5 / 12 VAL A  15
ALA A  32
LEU A 129
ALA A  62
ASP A  65
 None
 0.86A 4v04B-5hmbA:
undetectable		 4v04B-5hmbA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5hmb AZI13
(Streptomyces
sahachiroi) 		5 / 11 ASN A  79
HIS A  52
VAL A  55
THR A 114
TRP A  34
 None
 1.37A 4ygfA-5hmbA:
undetectable		 4ygfA-5hmbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5hmb AZI13
(Streptomyces
sahachiroi) 		5 / 9 ASN A  79
HIS A  52
VAL A  55
THR A 114
TRP A  34
 None
 1.34A 4ygfF-5hmbA:
undetectable		 4ygfF-5hmbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5hmb AZI13
(Streptomyces
sahachiroi) 		5 / 12 ASN A  79
HIS A  52
VAL A  55
THR A 114
TRP A  34
 None
 1.29A 4yhaG-5hmbA:
undetectable		 4yhaG-5hmbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 5hmb AZI13
(Streptomyces
sahachiroi) 		4 / 6 ARG A 124
GLY A 125
THR A 114
VAL A  56
 None
 1.10A 5ysiA-5hmbA:
undetectable		 5ysiA-5hmbA:
20.50