SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CLA_A_CLMA221_0 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	5hmn	AAC3-I (uncultured bacterium)	5 / 10	THR A 22 PHE A 23 ALA A 26 LEU A 102 ILE A 98	None None COA A 201 ( 4.6A) None COA A 201 (-4.3A)	1.32A	1claA-5hmnA: undetectable	1claA-5hmnA: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_A_ASDA1224_1 (GLUTATHIONE S-TRANSFERASE A3)	5hmn	AAC3-I (uncultured bacterium)	4 / 7	TYR A 70 PHE A 52 LEU A 19 ALA A 54	None	1.17A	2vcvA-5hmnA: undetectable	2vcvA-5hmnA: 23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BMV_C_VLBC507_1 (TUBULIN BETA CHAIN TUBULIN ALPHA-1B CHAIN)	5hmn	AAC3-I (uncultured bacterium)	4 / 6	ASP A 86 PRO A 130 TYR A 135 LEU A 134	PG4 A 202 (-3.7A) COA A 201 (-3.9A) COA A 201 (-4.8A) COA A 201 (-3.9A)	1.15A	5bmvB-5hmnA: undetectable	5bmvB-5hmnA: 16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_2_BEZ2801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 BEZ-LEU-LEU)	5hmn	AAC3-I (uncultured bacterium)	4 / 4	LEU A 72 ARG A 113 ILE A 82 ILE A 53	None	1.34A	5dzk2-5hmnA: undetectable 5dzkM-5hmnA: undetectable 5dzkN-5hmnA: undetectable	5dzk2-5hmnA: 4.08 5dzkM-5hmnA: 22.64 5dzkN-5hmnA: 22.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CLA_A_CLMA221_0","TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE","5hmn","AAC3-I","uncultured bacterium",5,"THR A  22;PHE A  23;ALA A  26;LEU A 102;ILE A  98","None;None;COA A 201 ( 4.6A);None;COA A 201 (-4.3A)","1.32A","1claA-5hmnA:undetectable","1claA-5hmnA:21.40"],["2VCV_A_ASDA1224_1","GLUTATHIONE S-TRANSFERASE A3","5hmn","AAC3-I","uncultured bacterium",4,"TYR A  70;PHE A  52;LEU A  19;ALA A  54","None","1.17A","2vcvA-5hmnA:undetectable","2vcvA-5hmnA:23.50"],["5BMV_C_VLBC507_1","TUBULIN BETA CHAIN;TUBULIN ALPHA-1B CHAIN","5hmn","AAC3-I","uncultured bacterium",4,"ASP A  86;PRO A 130;TYR A 135;LEU A 134","PG4 A 202 (-3.7A);COA A 201 (-3.9A);COA A 201 (-4.8A);COA A 201 (-3.9A)","1.15A","5bmvB-5hmnA:undetectable","5bmvB-5hmnA:16.63"],["5DZK_2_BEZ2801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;BEZ-LEU-LEU","5hmn","AAC3-I","uncultured bacterium",4,"LEU A  72;ARG A 113;ILE A  82;ILE A  53","None","1.34A","5dzk2-5hmnA:undetectable;5dzkM-5hmnA:undetectable;5dzkN-5hmnA:undetectable","5dzk2-5hmnA:4.08;5dzkM-5hmnA:22.64;5dzkN-5hmnA:22.64"]]