SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 5hn1 INTERLEUKIN-37
(Homo
sapiens) 		4 / 8 SER A 169
ASP A 191
CYH A 122
ASP A 125
 None
 1.04A 3havA-5hn1A:
undetectable		 3havA-5hn1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5hn1 INTERLEUKIN-37
(Homo
sapiens) 		3 / 3 ASP A 125
LYS A 124
ASP A 123
 None
None
SO4  A 302 (-4.5A)
 0.85A 4a7tA-5hn1A:
undetectable		 4a7tA-5hn1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5hn1 INTERLEUKIN-37
(Homo
sapiens) 		4 / 8 PHE A  91
LEU A 133
VAL A 187
ILE A  62
 None
 1.01A 4l4cB-5hn1A:
undetectable		 4l4cB-5hn1A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 5hn1 INTERLEUKIN-37
(Homo
sapiens) 		5 / 9 LEU A  77
PHE A  60
GLU A  89
PHE A 203
LEU A 167
 None
 1.49A 4la0B-5hn1A:
undetectable		 4la0B-5hn1A:
15.38