SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		3 / 4 LYS A 173
ALA A 176
MET A 155
 None
 0.83A 1hk3A-5hnmA:
undetectable		 1hk3A-5hnmA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		4 / 6 ARG A 146
ASP A 195
ILE A 196
LEU A 212
 SO4  A 302 (-2.7A)
ZN  A 301 ( 2.2A)
None
None
 0.93A 2ya7B-5hnmA:
undetectable		 2ya7B-5hnmA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		4 / 5 TYR A 242
ILE A 196
LEU A 125
LEU A 128
 None
 0.95A 2zb7A-5hnmA:
undetectable		 2zb7A-5hnmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		4 / 7 ASP A 195
SER A 143
GLU A 153
ASP A 156
 ZN  A 301 ( 2.2A)
None
None
None
 1.26A 3bc9A-5hnmA:
undetectable		 3bc9A-5hnmA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		4 / 4 PRO A 183
THR A 185
GLY A 234
THR A 230
 None
 1.05A 3ib1A-5hnmA:
undetectable		 3ib1A-5hnmA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5hnm D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
(Enterococcus
faecalis) 		4 / 5 LEU A  91
TYR A 263
ALA A 250
ILE A 222
 None
 0.94A 4y03B-5hnmA:
undetectable		 4y03B-5hnmA:
21.20