SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5hnp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JZS_A_MRCA1301_1 (ISOLEUCYL-TRNA SYNTHETASE)	5hnp	ABC TRANSPORTER (Raoultella ornithinolytica)	5 / 11	GLY A 429 HIS A 432 GLY A 391 LEU A 323 ILE A 324	None	1.25A	1jzsA-5hnpA: undetectable	1jzsA-5hnpA: 12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWX_B_EPAB3_2 (PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA)))	5hnp	ABC TRANSPORTER (Raoultella ornithinolytica)	5 / 12	ILE A 380 VAL A 276 LEU A 281 ILE A 304 MET A 416	None	1.14A	3gwxB-5hnpA: undetectable	3gwxB-5hnpA: 20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S79_A_ASDA601_1 (CYTOCHROME P450 19A1)	5hnp	ABC TRANSPORTER (Raoultella ornithinolytica)	5 / 12	ILE A 336 PHE A 334 ILE A 304 ALA A 303 ASP A 411	None	1.09A	3s79A-5hnpA: undetectable	3s79A-5hnpA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JKV_A_ASDA602_1 (AROMATASE)	5hnp	ABC TRANSPORTER (Raoultella ornithinolytica)	5 / 12	ILE A 336 PHE A 334 ILE A 304 ALA A 303 ASP A 411	None	1.08A	5jkvA-5hnpA: undetectable	5jkvA-5hnpA: 17.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JZS_A_MRCA1301_1","ISOLEUCYL-TRNA SYNTHETASE","5hnp","ABC TRANSPORTER","Raoultella ornithinolytica",5,"GLY A 429;HIS A 432;GLY A 391;LEU A 323;ILE A 324","None","1.25A","1jzsA-5hnpA:undetectable","1jzsA-5hnpA:12.31"],["3GWX_B_EPAB3_2","PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR-DELTA))","5hnp","ABC TRANSPORTER","Raoultella ornithinolytica",5,"ILE A 380;VAL A 276;LEU A 281;ILE A 304;MET A 416","None","1.14A","3gwxB-5hnpA:undetectable","3gwxB-5hnpA:20.50"],["3S79_A_ASDA601_1","CYTOCHROME P450 19A1","5hnp","ABC TRANSPORTER","Raoultella ornithinolytica",5,"ILE A 336;PHE A 334;ILE A 304;ALA A 303;ASP A 411","None","1.09A","3s79A-5hnpA:undetectable","3s79A-5hnpA:17.50"],["5JKV_A_ASDA602_1","AROMATASE","5hnp","ABC TRANSPORTER","Raoultella ornithinolytica",5,"ILE A 336;PHE A 334;ILE A 304;ALA A 303;ASP A 411","None","1.08A","5jkvA-5hnpA:undetectable","5jkvA-5hnpA:17.50"]]