SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ho1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		3 / 3 LEU A 256
HIS A 230
ILE A 291
 None
 0.47A 1s9pB-5ho1A:
undetectable		 1s9pB-5ho1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		5 / 10 GLY A 237
HIS A 245
ALA A 219
HIS A 283
ILE A 235
 None
ZN  A 301 (-3.4A)
None
ZN  A 301 (-3.3A)
None
 1.33A 1utdQ-5ho1A:
undetectable
1utdR-5ho1A:
undetectable		 1utdQ-5ho1A:
20.37
1utdR-5ho1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		4 / 7 GLY A 237
HIS A 245
ASP A 247
ILE A 248
 None
ZN  A 301 (-3.4A)
ZN  A 301 (-2.1A)
None
 0.76A 3fi0E-5ho1A:
undetectable		 3fi0E-5ho1A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		4 / 7 GLY A 237
HIS A 245
ASP A 247
ILE A 248
 None
ZN  A 301 (-3.4A)
ZN  A 301 (-2.1A)
None
 0.84A 3fi0P-5ho1A:
undetectable		 3fi0P-5ho1A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		4 / 8 GLY A 237
HIS A 245
ASP A 247
ILE A 248
 None
ZN  A 301 (-3.4A)
ZN  A 301 (-2.1A)
None
 0.79A 3fi0Q-5ho1A:
undetectable		 3fi0Q-5ho1A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 5ho1 MAGNETOSOME PROTEIN
MAMB
(Magnetospira
sp.
QH-2) 		4 / 4 ILE A 272
VAL A 244
VAL A 282
ARG A 269
 None
 1.13A 4m6tA-5ho1A:
undetectable		 4m6tA-5ho1A:
20.21